Evidence map›Paper›PMID 37761976›Full record

ArticleInternational journal of molecular sciences2023

Cross-Activation of Regulatory T Cells by Self Antigens Limits Self-Reactive and Activated CD8

Eunjung Cho, Seongeun Han, Hyeon Seok Eom, Sang-Jin Lee, Chungyong Han, Rohit Singh, Seon-Hee Kim, Bo-Mi Park, Byoung-Gie Kim, Young H Kim and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Eunjung ChoSeverance Biomedical Science Institute, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Seongeun HanImmuno-Oncology Branch, Division of Rare and Refractory Cancer, National Cancer Center, Goyang 10408, Republic of Korea.
Hyeon Seok EomHematological Malignancy Center of the Hospital, National Cancer Center, Goyang 10408, Republic of Korea.
Sang-Jin LeeImmuno-Oncology Branch, Division of Rare and Refractory Cancer, National Cancer Center, Goyang 10408, Republic of Korea.
Chungyong HanImmuno-Oncology Branch, Division of Rare and Refractory Cancer, National Cancer Center, Goyang 10408, Republic of Korea.
Rohit SinghImmuno-Oncology Branch, Division of Rare and Refractory Cancer, National Cancer Center, Goyang 10408, Republic of Korea.
Seon-Hee KimImmuno-Oncology Branch, Division of Rare and Refractory Cancer, National Cancer Center, Goyang 10408, Republic of Korea.
Bo-Mi ParkBiomedicine Production Branch, Research Institute, National Cancer Center, Goyang 10408, Republic of Korea.
Byoung-Gie KimDepartment of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Republic of Korea.
Young H KimEutilex, Co., Ltd., Geumcheon-gu, Seoul 08594, Republic of Korea.
Byoung S KwonEutilex, Co., Ltd., Geumcheon-gu, Seoul 08594, Republic of Korea.
Ki Taek NamSeverance Biomedical Science Institute, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0001-5292-1280
Beom K ChoiImmuno-Oncology Branch, Division of Rare and Refractory Cancer, National Cancer Center, Goyang 10408, Republic of Korea.
National Cancer Center · KRYonsei University · KRSamsung Medical Center · KR

Funding

National Cancer Center of Korea NCC- 2110490National Cancer Center of Korea NCC-2212450National Research Foundation of Korea 2022R1A2C1005463National Research Foundation of Korea 2022R1C1C1003152National Research Foundation of Korea 2022R1C1C1010078
6 · The paper itself

Abstract

The interaction between regulatory T (Treg) cells and self-reactive T cells is a crucial mechanism for maintaining immune tolerance. In this study, we investigated the cross-activation of Treg cells by self-antigens and its impact on self-reactive CD8

Indexed as

CD8-Positive T-LymphocytesT-Lymphocytes, RegulatoryAutoantigensCD8 AntigensHistocompatibility AntigensMART-1 AntigenTumor Suppressor Protein p53AutoantigensCD8 AntigensHistocompatibility AntigensMART-1 AntigenTumor Suppressor Protein p53CD8+ T cellp53peripheral toleranceregulatory T cellsself-antigen

Identifiers

PMID37761976
PMCPMC10530955
OpenAlexW4386440306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.