Evidence map›Paper›PMID 37761936›Full record

ReviewGenes2023

The Role of MicroRNA in Graft-Versus-Host-Disease: A Review.

Martina Pitea, Filippo Antonio Canale, Gaetana Porto, Chiara Verduci, Giovanna Utano, Giorgia Policastro, Caterina Alati, Ludovica Santoro, Lucrezia Imbalzano, Massimo Martino

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Martina PiteaStem Cell Transplantation and Cellular Therapies Unit (CTMO), Department of Hemato-Oncology and Radiotherapy Grande Ospedale Metropolitano "Bianchi-Malacrino-Morelli", 89124 Reggio Calabria, Italy.ORCID 0000-0002-3982-4141
Filippo Antonio CanaleStem Cell Transplantation and Cellular Therapies Unit (CTMO), Department of Hemato-Oncology and Radiotherapy Grande Ospedale Metropolitano "Bianchi-Malacrino-Morelli", 89124 Reggio Calabria, Italy.ORCID 0000-0001-9400-5897
Gaetana PortoStem Cell Transplantation and Cellular Therapies Unit (CTMO), Department of Hemato-Oncology and Radiotherapy Grande Ospedale Metropolitano "Bianchi-Malacrino-Morelli", 89124 Reggio Calabria, Italy.ORCID 0000-0003-4739-349X
Chiara VerduciStem Cell Transplantation and Cellular Therapies Unit (CTMO), Department of Hemato-Oncology and Radiotherapy Grande Ospedale Metropolitano "Bianchi-Malacrino-Morelli", 89124 Reggio Calabria, Italy.ORCID 0000-0002-9671-5507
Giovanna UtanoStem Cell Transplantation and Cellular Therapies Unit (CTMO), Department of Hemato-Oncology and Radiotherapy Grande Ospedale Metropolitano "Bianchi-Malacrino-Morelli", 89124 Reggio Calabria, Italy.
Giorgia PolicastroStem Cell Transplantation and Cellular Therapies Unit (CTMO), Department of Hemato-Oncology and Radiotherapy Grande Ospedale Metropolitano "Bianchi-Malacrino-Morelli", 89124 Reggio Calabria, Italy.
Caterina AlatiHematology Unit, Department of Hemato-Oncology and Radiotherapy Grande Ospedale Metropolitano "Bianchi-Melacrino-Morelli", 89124 Reggio Calabria, Italy.
Ludovica SantoroStem Cell Transplantation and Cellular Therapies Unit (CTMO), Department of Hemato-Oncology and Radiotherapy Grande Ospedale Metropolitano "Bianchi-Malacrino-Morelli", 89124 Reggio Calabria, Italy.
Lucrezia ImbalzanoStem Cell Transplantation and Cellular Therapies Unit (CTMO), Department of Hemato-Oncology and Radiotherapy Grande Ospedale Metropolitano "Bianchi-Malacrino-Morelli", 89124 Reggio Calabria, Italy.
Massimo MartinoStem Cell Transplantation and Cellular Therapies Unit (CTMO), Department of Hemato-Oncology and Radiotherapy Grande Ospedale Metropolitano "Bianchi-Malacrino-Morelli", 89124 Reggio Calabria, Italy.ORCID 0000-0002-3987-419X
Azienda ospedaliera "Bianchi-Melacrino-Morelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a clinically challenging modality for the treatment of many hematologic diseases such as leukemia, lymphoma, and myeloma. Graft-versus-host disease (GVHD) is a common complication after allo-HSCT and remains a major cause of morbidity and mortality, limiting the success of a potentially curative transplant. Several microRNAs (miRNAs) have recently been shown to impact the biology of GVHD. They are molecular regulators involved in numerous processes during T-cell development, homeostasis, and activation, and contribute to the pathological function of T-cells during GvHD. Here, we review the key role of miRNAs contributing to the GvHD; their detection might be an interesting possibility in the early diagnosis and monitoring of disease.

Indexed as

Graft vs Host DiseaseHematopoietic Stem Cell TransplantationLymphomaMicroRNAsHumansTransplantation, HomologousMicroRNAsGVHDmiRNAsstem cell transplantation

Identifiers

PMID37761936
PMCPMC10530280
OpenAlexW4386744649

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.