Evidence map›Paper›PMID 37761918›Full record

ArticleGenes2023

Gene Expression Analysis of nc-RNAs in Bipolar and Panic Disorders: A Pilot Study.

Fabrizio Bella, Maria Rosaria Anna Muscatello, Angela D'Ascola, Salvatore Campo

Open access · goldAbstract read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Plasma miRNA Profiles in Chronically Treated Bipolar Disorder Patients: A Case-Control Study.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025
    Article
  6. Circulating long noncoding RNA: New frontiers in biomarker research for mood disorders.Genomic psychiatry : advancing science from genes to society · 2025
    Article
  7. Decoding serotonin: the molecular symphony behind depression.Frontiers in cellular neuroscience · 2025
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Fabrizio BellaPsychiatry Unit, Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy.ORCID 0000-0002-1527-1634
Maria Rosaria Anna MuscatelloPsychiatry Unit, Department of Biomedical Sciences and of Morphological and Functional Images, University of Messina, 98122 Messina, Italy.
Angela D'AscolaMolecular Biology Laboratory, Department of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy.ORCID 0000-0001-7530-1316
Salvatore CampoMolecular Biology Laboratory, Department of Biomedical Sciences and of Morphological and Functional Images, University of Messina, 98122 Messina, Italy.
University of Messina · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBipolar Disorder (BD) is a chronic, highly disabling mood disorder. Among the major comorbidities, Panic Disorder (PD) is often associated with BD. This could suggest a common genetic and pathophysiological background between these two conditions, as suggested by previous studies. Despite the widespread diffusion of these conditions, little is still known about the exact pathophysiological dynamics that underlies them. Non-coding RNAs have recently started to gain attention in psychiatry research, with several papers indicating the dysregulation of lncRNAs as a possible key factor in etiopathogenesis of several mental disorders. In the light of the above, the aim of this study is to evaluate the gene expression levels of

methodsthe experimental plan envisaged the recruitment of sixteen patients with a first diagnosis of type one or type two BD and ten patients with PD. Patients with medical and/or psychiatric comorbidities were excluded. Peripheral venous blood was collected both from patients and healthy controls. Each of the patients recruited for the study was prescribed with therapy. Serum ncRNAs levels were remeasured after 5 months of therapy.

results

conclusionsgene expression levels of the ncRNAs

Indexed as

Bipolar DisorderMicroRNAsPanic DisorderRNA, Long NoncodingGene Expression ProfilingHumansPilot ProjectsMicroRNAsRNA, Long Noncodingbipolar disordersmolecular geneticspanic disorder

Identifiers

PMID37761918
PMCPMC10530917
OpenAlexW4386601892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.