Evidence map›Paper›PMID 37761915›Full record

ArticleGenes2023

Association of

Jorge Velazquez-Roman, Uriel A Angulo-Zamudio, Nidia Leon-Sicairos, Hector Flores-Villaseñor, Miriam Benitez-Baez, Ana Espinoza-Salomón, Alejandra Karam-León, Hugo Villamil-Ramírez, Samuel Canizales-Quinteros, Luis Macías-Kauffer and 3 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jorge Velazquez-RomanSchool of Medicine, Autonomous University of Sinaloa, Culiacan Sinaloa 80019, Mexico.
Uriel A Angulo-ZamudioSchool of Medicine, Autonomous University of Sinaloa, Culiacan Sinaloa 80019, Mexico.ORCID 0000-0003-2733-0766
Nidia Leon-SicairosSchool of Medicine, Autonomous University of Sinaloa, Culiacan Sinaloa 80019, Mexico.ORCID 0000-0003-1470-3383
Hector Flores-VillaseñorSchool of Medicine, Autonomous University of Sinaloa, Culiacan Sinaloa 80019, Mexico.ORCID 0000-0001-9734-8019
Miriam Benitez-BaezPrograma de Doctorado, Posgrado Integral en Biotecnología, FCQB, UAS, Culiacan Sinaloa 80013, Mexico.
Ana Espinoza-SalomónSchool of Medicine, Autonomous University of Sinaloa, Culiacan Sinaloa 80019, Mexico.
Alejandra Karam-LeónPrograma de Doctorado, Posgrado Integral en Biotecnología, FCQB, UAS, Culiacan Sinaloa 80013, Mexico.
Hugo Villamil-RamírezUnidad de Genómica de Poblaciones Aplicada a la Salud, Facultad de Química, UNAM/INMEGEN, Mexico City 04510, Mexico.
Samuel Canizales-QuinterosUnidad de Genómica de Poblaciones Aplicada a la Salud, Facultad de Química, UNAM/INMEGEN, Mexico City 04510, Mexico.ORCID 0000-0002-4833-6932
Luis Macías-KaufferUnidad de Genómica de Poblaciones Aplicada a la Salud, Facultad de Química, UNAM/INMEGEN, Mexico City 04510, Mexico.ORCID 0000-0002-3080-2835
Jose Monroy-HigueraPrograma de Doctorado, Posgrado Integral en Biotecnología, FCQB, UAS, Culiacan Sinaloa 80013, Mexico.
Erika Acosta-SmithSchool of Medicine, Autonomous University of Sinaloa, Culiacan Sinaloa 80019, Mexico.ORCID 0000-0001-8313-6699
Adrian Canizalez-RomanSchool of Medicine, Autonomous University of Sinaloa, Culiacan Sinaloa 80019, Mexico.ORCID 0000-0001-8605-0639
Universidad Autónoma de Sinaloa · MXNational Institute of Genomic Medicine · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic diseases, including obesity, diabetes, and metabolic syndrome, are among the most important public health challenges worldwide. Metabolic diseases are classified as multifactorial diseases in which genetic variants such as single-nucleotide polymorphisms (SNPs) may play an important role. The present study aimed to identify associations linking allelic variants of the

methodsBlood samples were collected from 523 subjects, including 247 with normal weight, 276 with obesity, and 147 with metabolic syndrome. Anthropometric and biochemical characteristics were recorded, and single-nucleotide polymorphisms (SNPs) were genotyped by real-time PCR.

results

conclusionsThe associations found in this study, mainly between allelic variants of

Indexed as

Metabolic SyndromeAdultAllelesGenotypeHumansMexicoObesityPPAR gammaProprotein Convertase 1PCSK1 protein, humanPPAR gammaProprotein Convertase 1metabolic syndromeobesityPCSK1PPARG1SNP

Identifiers

PMID37761915
PMCPMC10531047
OpenAlexW4386542019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.