Evidence map›Paper›PMID 37761353›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Ultrasonographic Presentation and Anatomic Distribution of Lung Involvement in Patients with Rheumatoid Arthritis.

Marie Vermant, Alexandros Kalkanis, Tinne Goos, Heleen Cypers, Nico De Crem, Barbara Neerinckx, Veerle Taelman, Patrick Verschueren, Wim A Wuyts

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Marie VermantLaboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department of Chronic Diseases and Metabolism, Katholieke Universiteit Leuven, Herestraat 49, 3000 Leuven, Belgium.ORCID 0000-0001-8546-8638
Alexandros KalkanisDepartment of Pulmonology, University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-1740-6782
Tinne GoosLaboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department of Chronic Diseases and Metabolism, Katholieke Universiteit Leuven, Herestraat 49, 3000 Leuven, Belgium.ORCID 0000-0002-8081-333X
Heleen CypersDepartment of Rheumatology, University Hospitals Leuven, 3000 Leuven, Belgium.
Nico De CremDepartment of Pulmonology, University Hospitals Leuven, 3000 Leuven, Belgium.
Barbara NeerinckxDepartment of Rheumatology, University Hospitals Leuven, 3000 Leuven, Belgium.
Veerle TaelmanDepartment of Rheumatology, University Hospitals Leuven, 3000 Leuven, Belgium.
Patrick VerschuerenDepartment of Rheumatology, University Hospitals Leuven, 3000 Leuven, Belgium.
Wim A WuytsLaboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department of Chronic Diseases and Metabolism, Katholieke Universiteit Leuven, Herestraat 49, 3000 Leuven, Belgium.
KU Leuven · BE

Funding

Research Foundation - Flanders SE14324N
6 · The paper itself

Abstract

backgroundRheumatoid arthritis (RA) is a chronic auto-immune disease, typically affecting the joints, which can also present with lung involvement (pleuritis, interstitial lung disease, pulmonary nodules, etc.). Lung ultrasound (LUS) is an upcoming tool in the detection of these pulmonary manifestations.

methodsWe performed a 72-window LUS in 75 patients presenting to the outpatient rheumatology clinic and describe the abnormalities (presence of B-lines (vertical comet-tail artefacts), pleural abnormalities, pleural effusions, and subpleural nodules) on lung ultrasound. We created a topological mapping of the number of B-lines per intercostal zone.

resultsWe observed pleural effusions, pleural abnormalities, and pleural nodules in, respectively, 1.3%, 45.3%, and 14% of patients. There were 35 (46.7%) patients who had less than 5 B-lines, 15 (20%) patients who had between 5 and 10 B-lines, 11 (14.6%) between 10 and 20, 10 (13.3%) between 20 and 50, 1 (1.3%) between 50 and 100, and 3 (4%) of patients who had more than 100 B-lines.

conclusionsLUS in patients with RA shows an array of abnormalities ranging from interstitial syndromes to pleural abnormalities, subpleural nodules, and pleural effusions. Hotspots for the presence of B-lines are situated bilaterally in the posterior subscapular regions, as well as the anterior right mid-clavicular region.

Indexed as

extra-articular manifestations of rheumatoid arthritislung ultrasoundrheumatoid-arthritis-associated interstitial lung disease

Identifiers

PMID37761353
PMCPMC10529908
OpenAlexW4386849556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.