ArticleDiagnostics (Basel, Switzerland)2023
Pulmonary Sarcoidosis and Immune Dysregulation: A Pilot Study on Possible Correlation.
Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 7 citations in OpenAlex.
- Exploring sarcoidosis via nailfold capillaroscopy: A window into the disease's microvascular landscape.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025Article
- Cardiac sarcoidosis recurrence post-heart transplant: A critical literature and case report.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025Article
- Associations of peripheral blood lymphopenia to disease course, treatment and TNF-α in sarcoidosis.Respiratory research · 2025Article
- The Frequency of Mediastinal Lymph Node Calcification in Sarcoidosis Patients and the Influencing Factors.Medicina (Kaunas, Lithuania) · 2024Article
- Rheumatologic Perspectives on Sarcoidosis: Predicting Sarcoidosis-Associated Arthritis Through Comprehensive Clinical and Laboratory Assessment.Journal of clinical medicine · 2024Article
- Autoantibodies in sarcoidosis: Innocent bystander or promising biomarker for organ involvement?Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2024Article
- Nailfold Video-Capillaroscopy in Sarcoidosis: New Perspectives and Challenges.Tomography (Ann Arbor, Mich.) · 2024Review
- Is YouTube a sufficient source of information on Sarcoidosis?Respiratory research · 2024Article
- Cardiopulmonary exercise testing complements both spirometry and nuclear imaging for assessing sarcoidosis stage and for monitoring disease activity.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2024Article
- Advances in Diagnostics and Management of Respiratory System Diseases.Diagnostics (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
19 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSarcoidosis is a systemic inflammatory disease characterized by an altered inflammatory response.
objectiveThe aim of this study was to evaluate whether immune system alterations detected by lymphocyte typing in peripheral blood correlate with the severity of sarcoidosis, calculated according to two separate severity scores proposed by Wasfi in 2006 and Hamzeh in 2010. MATERIALS AND
methodsEighty-one patients were recruited, and clinical data and laboratory tests at the time of diagnosis were obtained in order to assess the severity index score and investigate any statistically significant correlation with the cytofluorimetry data.
resultsOur data demonstrated that none of the two scores show an association with the level of total lymphocytes or lymphocyte subclasses. LIMITATIONS: First of all, the sample taken into consideration is small. The assessment was performed only at disease onset and not during the disease. Furthermore, the severity scores do not take into account disease activity (measured by PET/CT or gallium scintigraphy).
conclusionsLymphocyte subpopulation values at the time of diagnosis do not appear to correlate with disease severity at onset.
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