Evidence map›Paper›PMID 37761200›Full record

ReviewFoods (Basel, Switzerland)2023

Evidence for the Beneficial Effects of Brazilian Native Fruits and Their By-Products on Human Intestinal Microbiota and Repercussions on Non-Communicable Chronic Diseases-A Review.

Maiara da Costa Lima, Heloísa Maria Almeida do Nascimento, Jaielison Yandro Pereira da Silva, José Luiz de Brito Alves, Evandro Leite de Souza

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06394531 (Jaboticaba), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06394531 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Jaboticaba (Plinia Cauliflora) as a Strategy to Modulate Inflammation, Oxidative Stress, and Gut Dysbiosis in Patients With Chronic Kidney Disease

TypeinterventionalSponsorUniversidade Federal FluminenseRan2026 to 2028Enrolled30ConditionsChronic Kidney DiseasesArmsJaboticaba Peel Extract, Placebo
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Effects of Araticum (Food science & nutrition · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Maiara da Costa LimaDepartment of Nutrition, Health Science Center, Federal University of Paraíba, João Pessoa 58051-900, PB, Brazil.ORCID 0000-0001-6261-0128
Heloísa Maria Almeida do NascimentoDepartment of Nutrition, Health Science Center, Federal University of Paraíba, João Pessoa 58051-900, PB, Brazil.
Jaielison Yandro Pereira da SilvaDepartment of Nutrition, Health Science Center, Federal University of Paraíba, João Pessoa 58051-900, PB, Brazil.
José Luiz de Brito AlvesDepartment of Nutrition, Health Science Center, Federal University of Paraíba, João Pessoa 58051-900, PB, Brazil.ORCID 0000-0003-4696-3809
Evandro Leite de SouzaDepartment of Nutrition, Health Science Center, Federal University of Paraíba, João Pessoa 58051-900, PB, Brazil.ORCID 0000-0003-4927-9383
Universidade Federal da Paraíba · BR

Funding

Fundação de Apoio à Pesquisa do Estado da Paraíba 001
6 · The paper itself

Abstract

Non-communicable chronic diseases (NCDs) are the most widespread cause of mortality worldwide. Intestinal microbiota balance can be altered by changes in the abundance and/or diversity of intestinal microbiota, indicating a role of intestinal microbiota in NCD development. This review discusses the findings of in vitro studies, pre-clinical studies and clinical trials on the effects of Brazilian native fruits, their by-products, as well as their bioactive compounds on human intestinal microbiota and NCD. The major bioactive compounds in Brazilian native fruits and their by-products, and the impacts of their administration on outcomes linked to intestinal microbiota modulation are discussed. Mechanisms of intestinal microbiota affecting NCD could be linked to the modulation of absorption and energy balance, immune and endocrine systems, and inflammatory response. Brazilian native fruits, such as acerola, açaí, baru, buriti, guava, jabuticaba, juçara, and passion fruit, have several bioactive compounds, soluble and insoluble fibers, and a variety of phenolic compounds, which are capable of changing these key mechanisms. Brazilian native fruits and their by-products can help to promote positive intestinal and systemic health benefits by driving alterations in the composition of the human intestinal microbiota, and increasing the production of distinct short-chain fatty acids and phenolic metabolites, thereby enhancing intestinal integrity and homeostasis. Evidence from available literature shows that the modulatory impacts of Brazilian native fruits and their by-products on the composition and metabolic activity of the intestinal microbiota could improve several clinical repercussions associated with NCD, reinforcing the influence of intestinal microbiota in extra-intestinal outcomes.

Indexed as

bioactive compoundschronic diseasesfruitfunctional foodsintestinal microbiome

Identifiers

PMID37761200
PMCPMC10527964
OpenAlexW4386895702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.