Evidence map›Paper›PMID 37761116›Full record

ArticleFoods (Basel, Switzerland)2023

Integrated Transcriptomics and Metabolomics Reveal the Mechanism of Alliin in Improving Hyperlipidemia.

Min Zhang, Xiaoying Zou, Yixuan Du, Zhuangguang Pan, Fangqing He, Yuanming Sun, Meiying Li

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Hypoglycemic, Hypolipidemic, and Antioxidant Effect ofInternational journal of applied & basic medical research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Min ZhangGuangdong Provincial Key Lab of Food Safety and Quality, South China Agricultural University, Guangzhou 510642, China.
Xiaoying ZouGuangdong Provincial Key Lab of Food Safety and Quality, South China Agricultural University, Guangzhou 510642, China.
Yixuan DuGuangdong Provincial Key Lab of Food Safety and Quality, South China Agricultural University, Guangzhou 510642, China.
Zhuangguang PanGuangdong Provincial Key Lab of Food Safety and Quality, South China Agricultural University, Guangzhou 510642, China.
Fangqing HeGuangdong Provincial Key Lab of Food Safety and Quality, South China Agricultural University, Guangzhou 510642, China.
Yuanming SunGuangdong Provincial Key Lab of Food Safety and Quality, South China Agricultural University, Guangzhou 510642, China.
Meiying LiGuangdong Provincial Key Lab of Food Safety and Quality, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0002-5902-044X
South China Agricultural University · CN

Funding

National Museum of Natural Science No. 31801540
6 · The paper itself

Abstract

This research aims to assess the anti-hyperlipidemia effects of alliin in vivo and its potential mechanisms through transcriptomics and metabolomics analysis. A hyperlipidemia mode was established in C57BL/6 mice fed a high-fat diet, and the related physiological parameters of the animals were recorded. Serum TC and MDA in livers significantly decreased by 12.34% and 29.59%, respectively, and SOD and CAT in livers significantly increased by 40.64% and 39.05%, respectively, after high doses of alliin interventions. In total, 148 significantly different genes, particularly

Indexed as

alliinhyperlipidemiametabolomicstranscriptomics

Identifiers

PMID37761116
PMCPMC10528980
OpenAlexW4386711335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.