Evidence map›Paper›PMID 37761008›Full record

ArticleBiomedicines2023

Cristina Membrive-Jiménez, Sayleth Vieira-Maroun, Noelia Márquez-Pete, Yasmin Cura, Cristina Pérez-Ramírez, Jesús Tercedor-Sánchez, Alberto Jiménez-Morales, María Del Carmen Ramírez-Tortosa

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Cristina Membrive-JiménezPharmacogenetics Unit, Pharmacy Service, University Hospital Virgen de las Nieves, 18014 Granada, Spain.
Sayleth Vieira-MarounPharmacogenetics Unit, Pharmacy Service, University Hospital Virgen de las Nieves, 18014 Granada, Spain.
Noelia Márquez-PetePharmacogenetics Unit, Pharmacy Service, University Hospital Virgen de las Nieves, 18014 Granada, Spain.
Yasmin CuraPharmacogenetics Unit, Pharmacy Service, University Hospital Virgen de las Nieves, 18014 Granada, Spain.ORCID 0000-0001-5038-0708
Cristina Pérez-RamírezPharmacogenetics Unit, Pharmacy Service, University Hospital Virgen de las Nieves, 18014 Granada, Spain.ORCID 0000-0002-3511-1312
Jesús Tercedor-SánchezDermatology Service, University Hospital Virgen de las Nieves, 18014 Granada, Spain.ORCID 0000-0002-1548-594X
Alberto Jiménez-MoralesHospital Pharmacy Department, University Hospital Virgen de las Nieves, 18014 Granada, Spain.
María Del Carmen Ramírez-TortosaDepartment of Biochemistry and Molecular Biology II, Faculty of Pharmacy, University of Granada, 18011 Granada, Spain.ORCID 0000-0002-7999-0881
Hospital Universitario Virgen de las Nieves · ESUniversidad de Granada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMethotrexate (MTX) is one of the most extensively used drugs in the treatment of moderate-to-severe psoriasis (PS). However, it frequently must be suspended owing to the toxicity in certain patients.

objectiveTo evaluate the influence of

methodsRetrospective cohort study with 101 patients. Five single-nucleotide polymorphisms (SNPs) were genotyped using real-time polymerase chain reaction with TaqMan probes.

resultsPatients carrying

conclusion

Indexed as

adverse drug reactionsadverse eventsgenetic polymorphismshepatotoxicitymethotrexatepharmacogeneticspsoriasistoxicity

Identifiers

PMID37761008
PMCPMC10526923
OpenAlexW4386864466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.