Evidence map›Paper›PMID 37760869›Full record

ArticleBiomedicines2023

Exploring the Synthetic Chemistry of Phenyl-3-(5-aryl-2-furyl)- 2-propen-1-ones as Urease Inhibitors: Mechanistic Approach through Urease Inhibition, Molecular Docking and Structure-Activity Relationship.

Miraj Fatima, Samina Aslam, Ansa Madeeha Zafar, Ali Irfan, Misbahul Ain Khan, Muhammad Ashraf, Shah Faisal, Sobia Noreen, Gamal A Shazly, Bakht Ramin Shah and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Miraj FatimaDepartment of Chemistry, The Women University, Multan 66000, Pakistan.ORCID 0000-0003-3541-2796
Samina AslamDepartment of Chemistry, The Women University, Multan 66000, Pakistan.
Ansa Madeeha ZafarDepartment of Chemistry, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.ORCID 0000-0001-6277-6486
Ali IrfanDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0002-8977-3303
Misbahul Ain KhanDepartment of Chemistry, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
Muhammad AshrafDepartment of Biotechnology and Biochemistry, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
Shah FaisalDepartment of Chemistry, Islamia College University Peshawar, Peshawar 25120, Pakistan.ORCID 0000-0002-5105-6982
Sobia NoreenInstitute of Chemistry, University of Sargodha, Sargodha 40100, Pakistan.ORCID 0000-0002-0815-2223
Gamal A ShazlyDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Bakht Ramin ShahSkin Barrier Research Group, Faculty of Pharmacy in Hradec Králové, Charles University, 500 05 Hradec Králové, Czech Republic.ORCID 0000-0002-7078-1434
Yousef A Bin JardanDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0003-3302-4036
Islamia University of Bahawalpur · PKKing Saud University · SACharles University · CZGovernment College University, Faisalabad · PKIslamia College University · PKThe Women University Multan · PKUniversity of Sargodha · PK

Funding

The Researchers Supporting Project Number (RSP2023R457), King Saud University, Riyadh, Saudi Arabia. Researchers Supporting Project Number (RSP2023R457)
6 · The paper itself

Abstract

Furan chalcone scaffolds belong to the most privileged and promising oxygen-containing heterocyclic class of compounds, which have a wide spectrum of therapeutic applications in the field of pharmaceutics, pharmacology, and medicinal chemistry. This research described the synthesis of a series of twelve novel and seven reported furan chalcone (conventional synthetic approach) analogues

Indexed as

Claisen–Schmidt condensationfuran carbaldehydefuran chalconesmolecular dockingSARurease inhibition

Identifiers

PMID37760869
PMCPMC10525509
OpenAlexW4386304078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.