Evidence map›Paper›PMID 37760758›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Antimicrobial Peptides (AMP) in the Cell-Free Culture Media of

András Fodor, Claudia Hess, Petra Ganas, Zsófia Boros, János Kiss, László Makrai, Károly Dublecz, László Pál, László Fodor, Anna Sebestyén and 6 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Tropical medicine and infectious disease · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 4 countries.

András FodorDepartment of Genetics, Institute of Biology, Eötvös Loránd University, Pázmány Péter. sétány 1C, H-1117 Budapest, Hungary.ORCID 0000-0003-3495-0154
Claudia HessClinic for Poultry and Fish Medicine, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine (Vetmeduni Vienna), 1210 Vienna, Austria.ORCID 0000-0002-3535-5157
Petra GanasClinic for Poultry and Fish Medicine, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine (Vetmeduni Vienna), 1210 Vienna, Austria.
Zsófia BorosDepartment of Genetics, Institute of Biology, Eötvös Loránd University, Pázmány Péter. sétány 1C, H-1117 Budapest, Hungary.
János KissAgribiotechnology and Precision Breeding for Food Security National Laboratory, Department of Microbiology and Applied Biotechnology, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, Páter Károly utca 1, H-2100 Gödöllő, Hungary.ORCID 0000-0002-0506-5474
László MakraiAutovakcina Kft., H-1171 Budapest, Hungary.
Károly DubleczInstitute of Physiology and Nutrition, Georgikon Campus, Hungarian University of Agriculture and Life Sciences (MATE), Deák Ferenc utca 16, H-8360 Keszthely, Hungary.ORCID 0000-0001-6913-219X
László PálInstitute of Physiology and Nutrition, Georgikon Campus, Hungarian University of Agriculture and Life Sciences (MATE), Deák Ferenc utca 16, H-8360 Keszthely, Hungary.ORCID 0000-0001-9838-6703
László FodorDepartment of Microbiology and Infectious Diseases, University of Veterinary Medicine, H-1143 Budapest, Hungary.ORCID 0000-0003-2711-0229
Anna SebestyénFirst Department of Pathology and Experimental Cancer Research, Semmelweis University, H-1085 Budapest, Hungary.
Michael G KleinUSDA-ARS & Department of Entomology, The Ohio State University, 13416 Claremont Ave, Cleveland, OH 44130, USA.
Eustachio TarascoDepartment of Soil, Plant and Food Sciences, University of Bari "Aldo Moro", Via Amendola 165/A, 70126 Bari, Italy.ORCID 0000-0001-6310-186X
Manjusha M KulkarniDivision of Infectious Diseases, Department of Internal Medicine, The Ohio State University, Columbus, OH 43210, USA.
Bradford S McGwireDivision of Infectious Diseases, Department of Internal Medicine, The Ohio State University, Columbus, OH 43210, USA.
Tibor VellaiDepartment of Genetics, Institute of Biology, Eötvös Loránd University, Pázmány Péter. sétány 1C, H-1117 Budapest, Hungary.
Michael HessClinic for Poultry and Fish Medicine, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine (Vetmeduni Vienna), 1210 Vienna, Austria.ORCID 0000-0002-6991-0120
Eötvös Loránd University · HUMagyar Agrár- és Élettudományi Egyetem · HUThe Ohio State University · USUniversity of Veterinary Medicine Vienna · ATSemmelweis University · HUUniversity of Bari Aldo Moro · ITUniversity of Veterinary Medicine · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-microbial peptides provide a powerful toolkit for combating multidrug resistance. Combating eukaryotic pathogens is complicated because the intracellular drug targets in the eukaryotic pathogen are frequently homologs of cellular structures of vital importance in the host organism. The entomopathogenic bacteria (EPB), symbionts of entomopathogenic-nematode species, release a series of non-ribosomal templated anti-microbial peptides. Some may be potential drug candidates. The ability of an entomopathogenic-nematode/entomopathogenic bacterium symbiotic complex to survive in a given polyxenic milieu is a coevolutionary product. This explains that those gene complexes that are responsible for the biosynthesis of different non-ribosomal templated anti-microbial protective peptides (including those that are potently capable of inactivating the protist mammalian pathogen

Indexed as

CFCM (cell-free conditioned culture media)entomopathogenic nematode-symbiont bacteria (EPB)extracellular avian pathogensHistomonas meleagridiskinetoplastid protozoa parasiteLeishmanianon-ribosomal anti-microbial peptides (NR-AMP)Photorhabdus (P. luminescens TT01)probiotic potentialX. budapestensisXenorhabdusX. innexiiX. szentirmaii

Identifiers

PMID37760758
PMCPMC10525888
OpenAlexW4386895577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.