Evidence map›Paper›PMID 37760726›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Clonal, Plasmidic and Genetic Diversity of Multi-Drug-Resistant Enterobacterales from Hospitalized Patients in Tripoli, Libya.

Nada Elgriw, Véronique Métayer, Antoine Drapeau, Pauline François, Sana Azaiez, Maha Mastouri, Hajer Rhim, Adam Elzagheid, Najeeb Soufiyah, Jean-Yves Madec and 3 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 65% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Nada ElgriwDepartment of Microbiology, Libyan Biotechnology Reseaerch Center, Tripoli P.O. Box 30313, Libya.ORCID 0000-0001-6383-2806
Véronique MétayerUnité Antibiorésistance et Virulence Bactériennes, ANSES-Université de Lyon, 69007 Lyon, France.
Antoine DrapeauUnité Antibiorésistance et Virulence Bactériennes, ANSES-Université de Lyon, 69007 Lyon, France.
Pauline FrançoisUnité Antibiorésistance et Virulence Bactériennes, ANSES-Université de Lyon, 69007 Lyon, France.
Sana AzaiezLaboratoire de Recherche Biophysique Métabolique et Pharmacologie Appliquée, Faculté de Médecine Ibn Al Jazzar Sousse, Université de Sousse, LR12ES02, Sousse 4002, Tunisia.
Maha MastouriFaculty of pharmacy Monastir, Doctoral commission in Pharmaceutical Sciences, University of Monastir, Monastir 5000, Tunisia.ORCID 0000-0003-3630-5255
Hajer RhimFaculty of pharmacy Monastir, Doctoral commission in Pharmaceutical Sciences, University of Monastir, Monastir 5000, Tunisia.
Adam ElzagheidDepartment of Genetic Engineering, Libyan Biotechnology Reseaerch Center, Tripoli P.O. Box 30313, Libya.
Najeeb SoufiyahMedical Microbiology and Immunology Department, Faculty of Pharmacy, University of Tripoli, Tripoli P.O. Box 13275, Libya.
Jean-Yves MadecUnité Antibiorésistance et Virulence Bactériennes, ANSES-Université de Lyon, 69007 Lyon, France.
Cherifa ChaouchFaculty of pharmacy Monastir, Doctoral commission in Pharmaceutical Sciences, University of Monastir, Monastir 5000, Tunisia.ORCID 0000-0003-1385-6951
Wejdene MansourLaboratoire de Recherche Biophysique Métabolique et Pharmacologie Appliquée, Faculté de Médecine Ibn Al Jazzar Sousse, Université de Sousse, LR12ES02, Sousse 4002, Tunisia.
Marisa HaenniUnité Antibiorésistance et Virulence Bactériennes, ANSES-Université de Lyon, 69007 Lyon, France.ORCID 0000-0003-1333-5603
Université Claude Bernard Lyon 1 · FRUniversity of Monastir · TNUniversity of Sousse · TNUniversity of Tripoli · LY

Funding

French Agency for Food, Environmental and Occupational Health & Safety no grant number
6 · The paper itself

Abstract

Resistance to extended-spectrum cephalosporins (ESC) and carbapenems in Enterobacterales is a major issue in public health. Carbapenem resistance in particular is associated with increased morbidity and mortality. Moreover, such resistance is often co-harbored with resistance to non-beta-lactam antibiotics, and pathogens quickly become multi-drug-resistant (MDR). Only a few studies have been published on AMR in Libyan hospitals, but all reported worrisome results. Here, we studied 54 MDR isolates that were collected from 49 patients at the Tripoli University Hospital between 2019 and 2021. They were characterized using phenotypic methods, PCR and PFGE, and a sub-set of isolates were short- and long-read whole-genome sequenced. The results showed the frequent occurrence of

Indexed as

amikacincarbapenemcolistinE. coliKPC-2K. pneumoniaeNDM-1nosocomial infectionOXA-48

Identifiers

PMID37760726
PMCPMC10525897
OpenAlexW4386608572

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.