Evidence map›Paper›PMID 37760722›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Procalcitonin-Based Antibiotic Use for Neonatal Early-Onset Bacterial Infections: Pre- and Post-Intervention Clinical Study.

Hidetoshi Go, Nobuhiko Nagano, Yuki Sato, Daichi Katayama, Koichiro Hara, Takuya Akimoto, Takayuki Imaizumi, Ryoji Aoki, Midori Hijikata, Ayako Seimiya and 2 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hidetoshi GoDepartment of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo 1738610, Japan.
Nobuhiko NaganoDepartment of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo 1738610, Japan.ORCID 0000-0002-0890-1626
Yuki SatoDepartment of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo 1738610, Japan.
Daichi KatayamaDepartment of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo 1738610, Japan.
Koichiro HaraDepartment of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo 1738610, Japan.
Takuya AkimotoDepartment of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo 1738610, Japan.
Takayuki ImaizumiDepartment of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo 1738610, Japan.
Ryoji AokiDepartment of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo 1738610, Japan.
Midori HijikataDepartment of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo 1738610, Japan.
Ayako SeimiyaDepartment of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo 1738610, Japan.
Aya OkahashiDepartment of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo 1738610, Japan.
Ichiro MoriokaDepartment of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo 1738610, Japan.ORCID 0000-0002-5685-2670

Funding

Nihon University Research Grant for 2022 and the Japan Agency for Medical Research and De-velopment (grant numbers: JP 23fk0108682).
6 · The paper itself

Abstract

We previously reported the 95th percentile cutoff value of the serum procalcitonin (PCT) reference curve for diagnosing early-onset bacterial infection. We aimed to verify the effectivity of these novel diagnostic criteria by comparing antibiotic use and incidence of early-onset bacterial infection between pre- and post-introduction periods. We included newborns admitted to our neonatal intensive care unit who underwent blood tests within 72 h after birth between 2018 and 2022. The neonates were divided into the pre-intervention (admitted before the introduction,

Indexed as

antibiotic resistanceantibioticsappropriate use of antibioticsdays of antibiotic therapyearly-onset bacterial infectionprocalcitonin

Identifiers

PMID37760722
PMCPMC10525994

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.