Evidence map›Paper›PMID 37760680›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Responding to Urinary Tract Infection Symptoms in England's Community Pharmacies.

Sejal Parekh, Kieran Hand, Lingqian Xu, Victoria Roberts, Fionna Pursey, Diane Ashiru-Oredope, Donna M Lecky

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sejal ParekhPrimary, Community and Personalised Care Directorate, NHS England, London SE1 8UG, UK.ORCID 0000-0002-3135-7710
Kieran HandAMR Programme, Medical Directorate, NHS England, Leeds LS2 7UE, UK.ORCID 0000-0002-3834-2415
Lingqian XuPrimary, Community and Personalised Care Directorate, NHS England, London SE1 8UG, UK.ORCID 0000-0002-8707-0102
Victoria RobertsPrimary, Community and Personalised Care Directorate, NHS England, London SE1 8UG, UK.
Fionna PurseyHCAI, Fungal, AMR, AMU & Sepsis Division, UK Health Security Agency, London SW1P 3HX, UK.
Diane Ashiru-OredopeHCAI, Fungal, AMR, AMU & Sepsis Division, UK Health Security Agency, London SW1P 3HX, UK.
Donna M LeckyHCAI, Fungal, AMR, AMU & Sepsis Division, UK Health Security Agency, London SW1P 3HX, UK.ORCID 0000-0002-1223-9356
NHS EnglandUK Health Security Agency · GBNHS Digital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most urinary tract infections (UTIs) are self-limiting and frequently present in primary care; it is common for patients to seek symptom relief. The TARGET Treating Your Infection (TYI) leaflet was used to respond to UTI symptoms for women under 65 years presenting in community pharmacies. The widespread use of these leaflets was incentivised as part of NHS England's Pharmacy Quality Scheme (PQS) 2022-23, between October 2022 and March 2023. The TARGET TYI leaflets are aimed to support appropriate antibiotic use and antimicrobial stewardship (AMS) as well as reducing the opportunity for resistance to develop. A total of 8363 community pharmacies completed the AMS criteria within the PQS and collectively submitted data for 104,142 patients presenting with UTI symptoms. The majority, 77% (75,071), of (non-pregnant) women presented with none or only one of the three strongly predictive symptoms of dysuria, new nocturia, cloudy urine, and/or vaginal discharge and, therefore, were less likely to have a UTI, as outlined in the English UTI diagnostic guidance. Conversely, 23% (22,381) of women presented with two or more symptoms of dysuria, new nocturia, cloudy urine, and with no vaginal discharge and, therefore, they were more likely to have a UTI. The TARGET TYI UTI leaflets support community pharmacy teams to differentiate between symptoms more likely to be associated with UTIs and those that could be managed with self-care. The findings suggest that most women presenting to community pharmacies with urinary symptoms were likely to have self-limiting symptoms, and could be suitably managed with self-care, pain relief, and appropriate safety netting. Approximately one-third of patients were managed by community pharmacy team members without the need for referral to a pharmacist and one in five patients presented with escalation symptoms and were signposted to other healthcare settings. A total of 94% (97,452) of women received self-care advice of which 36% (37,565) were also provided with additional patient information leaflets.

Indexed as

antimicrobial resistanceantimicrobial stewardshipcommunity pharmacyincentivisationmedication safetypharmacy quality schemeprimary careTARGET Toolkiturinary tract infections

Identifiers

PMID37760680
PMCPMC10525945
OpenAlexW4386283076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.