ArticleAntibiotics (Basel, Switzerland)2023
Microbiological Profile of Fracture Related Infection at a UK Major Trauma Centre.
Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Clinical characteristics and risk factors of recurrence for Pseudomonas aeruginosa-associated fracture-related infection following surgical treatment : a 12-year retrospective cohort study.Bone & joint open · 2026Article
- Strategic considerations in the treatment of infected nonunion in the lower extremity: a narrative review.International journal of surgery (London, England) · 2026Article
- Predictors and Clinical Outcomes of Ciprofloxacin Resistance in Acute Gram-Negative Osteomyelitis: Insights from a Six-Year Retrospective Study.Infection and drug resistance · 2026Article
- Management of fracture-related infection in low-resource settings in Africa: recommendations and guidelines from an international expert group.Journal of bone and joint infection · 2026Article
- Exploring the Value of Paired Microbiology and Histology in Chronic Osteomyelitis and Fracture-Related Infections.Antibiotics (Basel, Switzerland) · 2025Article
- Article
- Fracture-Related Infections: Current Status and Perspectives from the International Society of Antimicrobial Chemotherapy.Antibiotics (Basel, Switzerland) · 2025Review
- Combination Antibiotic Therapy for Orthopedic Infections.Antibiotics (Basel, Switzerland) · 2025Review
- Outcomes Associated with Choice of Prophylactic Antibiotics in Open Fractures.The Journal of bone and joint surgery. American volume · 2025Article
- Assessing the efficacy of systemic antibiotics for biofilm-associated infection in an ovine model of simulated fracture-related infection.Journal of bone and joint infection · 2025Article
- A Comparison of Causative Pathogens in Bone and Prosthetic Joint Infections: Implications for Antimicrobial Therapy.Antibiotics (Basel, Switzerland) · 2024Article
- Management of Fracture-Related Infection in Conflict Zones: Lessons Learned from Medical Missions to Gaza.Antibiotics (Basel, Switzerland) · 2024Article
- The Microbiological Profile and Antibiotic Susceptibility of Fracture Related Infections in a Low Resource Setting Differ from High Resource Settings: A Cohort Study from Cameroon.Antibiotics (Basel, Switzerland) · 2024Article
- Tibial Fractures at High Risk of Infection Treated with Intramedullary Nailing: Do Nails with Antibacterial Coatings Make a Difference?JB & JS open accessArticle
- Clinical Outcome following Management of Severe Osteomyelitis due to Pin Site Infection.Strategies in trauma and limb reconstructionArticle
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fracture Related Infection (FRI) represents one of the biggest challenges for Trauma and Orthopaedic surgery. A better understanding of the microbiological profile should assist with decision-making and optimising outcomes. Our primary aim was to report on the microbiological profile of FRI cases treated over a six-year period at one of Europe's busiest trauma centres. Secondarily, we sought to correlate our findings with existing anti-microbiological protocols and report on diagnostic techniques employed in our practice. All adult cases of FRI treated in our institution between 2016 and 2021 were identified, retrospectively. We recorded patient demographics, diagnostic strategies, causative organisms and antibiotic susceptibilities. There were 330 infection episodes in 294 patients. A total of 463 potentially pathogenic organisms (78 different species) were identified from cultures, of which 57.2% were gram-positive and 39.7% gram-negative. Polymicrobial cultures were found in 33.6% of cases and no causative organism was found in 17.5%. The most prevalent organisms were
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