Evidence map›Paper›PMID 37760633›Full record

ReviewCancers2023

Image-Guided Precision Medicine in the Diagnosis and Treatment of Pheochromocytomas and Paragangliomas.

Gildas Gabiache, Charline Zadro, Laura Rozenblum, Delphine Vezzosi, Céline Mouly, Matthieu Thoulouzan, Rosine Guimbaud, Philippe Otal, Lawrence Dierickx, Hervé Rousseau and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Gildas GabiacheDepartment of Radiology, Rangueil University Hospital, 31400 Toulouse, France.
Charline ZadroDepartment of Radiology, Rangueil University Hospital, 31400 Toulouse, France.
Laura RozenblumDepartment of Nuclear Medicine, Sorbonne Université, AP-HP, Hôpital La Pitié-Salpêtrière, 75013 Paris, France.ORCID 0000-0002-6306-8008
Delphine VezzosiDepartment of Endocrinology, Rangueil University Hospital, 31400 Toulouse, France.
Céline MoulyDepartment of Endocrinology, Rangueil University Hospital, 31400 Toulouse, France.
Matthieu ThoulouzanDepartment of Surgery, Rangueil University Hospital, 31400 Toulouse, France.
Rosine GuimbaudDepartment of Oncology, Rangueil University Hospital, 31400 Toulouse, France.
Philippe OtalDepartment of Radiology, Rangueil University Hospital, 31400 Toulouse, France.
Lawrence DierickxDepartment of Nuclear Medicine, IUCT-Oncopole, 31059 Toulouse, France.ORCID 0000-0002-5274-4138
Hervé RousseauDepartment of Radiology, Rangueil University Hospital, 31400 Toulouse, France.
Christopher TrepanierNew York-Presbyterian Hospital/Department of Radiology, Columbia University Irving Medical Center, New York, NY 10032, USA.
Laurent DercleNew York-Presbyterian Hospital/Department of Radiology, Columbia University Irving Medical Center, New York, NY 10032, USA.ORCID 0000-0002-1322-0710
Fatima-Zohra MokraneDepartment of Radiology, Rangueil University Hospital, 31400 Toulouse, France.
Hôpital Rangueil · FRNewYork–Presbyterian Hospital · USInstitut universitaire du cancer de Toulouse Oncopole · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this comprehensive review, we aimed to discuss the current state-of-the-art medical imaging for pheochromocytomas and paragangliomas (PPGLs) diagnosis and treatment. Despite major medical improvements, PPGLs, as with other neuroendocrine tumors (NETs), leave clinicians facing several challenges; their inherent particularities and their diagnosis and treatment pose several challenges for clinicians due to their inherent complexity, and they require management by multidisciplinary teams. The conventional concepts of medical imaging are currently undergoing a paradigm shift, thanks to developments in radiomic and metabolic imaging. However, despite active research, clinical relevance of these new parameters remains unclear, and further multicentric studies are needed in order to validate and increase widespread use and integration in clinical routine. Use of AI in PPGLs may detect changes in tumor phenotype that precede classical medical imaging biomarkers, such as shape, texture, and size. Since PPGLs are rare, slow-growing, and heterogeneous, multicentric collaboration will be necessary to have enough data in order to develop new PPGL biomarkers. In this nonsystematic review, our aim is to present an exhaustive pedagogical tool based on real-world cases, dedicated to physicians dealing with PPGLs, augmented by perspectives of artificial intelligence and big data.

Indexed as

metabolic imagingparagangliomapheochromocytomaradiomic biomarkers

Identifiers

PMID37760633
PMCPMC10526298
OpenAlexW4386912957

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.