Evidence map›Paper›PMID 37760601›Full record

ArticleCancers2023

Insights into Melanoma Clinical Practice: A Perspective for Future Research.

Giang T Lam, Carmela Martini, Tiffany Brooks, Sarita Prabhakaran, Ashley M Hopkins, Ben S-Y Ung, Jingying Tang, Maria C Caruso, Robert D Brooks, Ian R D Johnson and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Amelanotic Melanoma-Biochemical and Molecular Induction Pathways.International journal of molecular sciences · 2024
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Giang T LamClinical and Health Sciences, University of South Australia, North Terrace, Adelaide, SA 5000, Australia.
Carmela MartiniClinical and Health Sciences, University of South Australia, North Terrace, Adelaide, SA 5000, Australia.ORCID 0000-0002-3891-7696
Tiffany BrooksAdelaide Medical School, University of Adelaide, North Terrace, Adelaide, SA 5000, Australia.
Sarita PrabhakaranCollege of Medicine and Public Health, Flinders University, Adelaide, SA 5042, Australia.ORCID 0000-0003-3252-2519
Ashley M HopkinsCollege of Medicine and Public Health, Flinders University, Adelaide, SA 5042, Australia.ORCID 0000-0001-7652-4378
Ben S-Y UngClinical and Health Sciences, University of South Australia, North Terrace, Adelaide, SA 5000, Australia.ORCID 0000-0001-7667-3648
Jingying TangClinical and Health Sciences, University of South Australia, North Terrace, Adelaide, SA 5000, Australia.
Maria C CarusoClinical and Health Sciences, University of South Australia, North Terrace, Adelaide, SA 5000, Australia.ORCID 0000-0001-7971-0651
Robert D BrooksClinical and Health Sciences, University of South Australia, North Terrace, Adelaide, SA 5000, Australia.ORCID 0000-0003-1535-8999
Ian R D JohnsonClinical and Health Sciences, University of South Australia, North Terrace, Adelaide, SA 5000, Australia.ORCID 0000-0001-7875-3510
Alexandra SorvinaClinical and Health Sciences, University of South Australia, North Terrace, Adelaide, SA 5000, Australia.ORCID 0000-0002-5918-3038
Shane M HickeyClinical and Health Sciences, University of South Australia, North Terrace, Adelaide, SA 5000, Australia.ORCID 0000-0002-3063-531X
Litsa KarageorgosClinical and Health Sciences, University of South Australia, North Terrace, Adelaide, SA 5000, Australia.ORCID 0000-0003-0732-8183
Sonja KlebeCollege of Medicine and Public Health, Flinders University, Adelaide, SA 5042, Australia.ORCID 0000-0002-8976-4714
John J O'LearyDepartment of Histopathology, Trinity College Dublin, D02 PN40 Dublin, Ireland.
Douglas A BrooksClinical and Health Sciences, University of South Australia, North Terrace, Adelaide, SA 5000, Australia.ORCID 0000-0001-9098-3626
Jessica M LoganClinical and Health Sciences, University of South Australia, North Terrace, Adelaide, SA 5000, Australia.ORCID 0000-0003-4046-6908

Funding

Rattigan Family Trust NAUniversity of South Australia NA
6 · The paper itself

Abstract

backgroundEarly diagnosis is the key to improving outcomes for patients with melanoma, and this requires a standardized histological assessment approach. The objective of this survey was to understand the challenges faced by clinicians when assessing melanoma cases, and to provide a perspective for future studies.

methodsBetween April 2022 and February 2023, national and international dermatologists, pathologists, general practitioners, and laboratory managers were invited to participate in a six-question online survey. The data from the survey were assessed using descriptive statistics and qualitative responses.

resultsA total of 54 responses were received, with a 51.4% (

conclusionsThe respondents indicated that the use of multiple IHC markers is essential to facilitate diagnostic accuracy in melanoma assessment. Survey responses indicate there is an urgent need to develop new biomarkers for clinical decision making at multiple critical intervention points.

Indexed as

biomarkerclinical practicediagnosismelanomapatient managementprognosissurveytherapeutic options

Identifiers

PMID37760601
PMCPMC10526186

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.