Evidence map›Paper›PMID 37760549›Full record

ArticleCancers2023

Cardiac Dose Predicts the Response to Concurrent Chemoradiotherapy in Esophageal Squamous Cell Carcinoma.

Yu-Chieh Ho, Yuan-Chun Lai, Hsuan-Yu Lin, Ming-Hui Ko, Sheng-Hung Wang, Shan-Jun Yang, Tsai-Wei Chou, Li-Chung Hung, Chia-Chun Huang, Tung-Hao Chang and 2 more

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yu-Chieh HoDepartment of Radiation Oncology, Changhua Christian Hospital, Changhua 500, Taiwan.ORCID 0000-0002-4905-1058
Yuan-Chun LaiDivision of Medical Physics, Department of Radiation Oncology, Changhua Christian Hospital, Changhua 500, Taiwan.
Hsuan-Yu LinDivision of Haematology/Oncology, Department of Internal Medicine, Changhua Christian Hospital, Changhua 500, Taiwan.
Ming-Hui KoDivision of Medical Physics, Department of Radiation Oncology, Changhua Christian Hospital, Changhua 500, Taiwan.
Sheng-Hung WangDepartment of Radiation Oncology, Lukang Christian Hospital, Changhua Christian Medical Foundation, Lukang 505, Taiwan.
Shan-Jun YangDepartment of Radiation Oncology, Changhua Christian Hospital, Changhua 500, Taiwan.
Tsai-Wei ChouDepartment of Radiation Oncology, Changhua Christian Hospital, Changhua 500, Taiwan.
Li-Chung HungDepartment of Radiation Oncology, Changhua Christian Hospital, Changhua 500, Taiwan.
Chia-Chun HuangDepartment of Radiation Oncology, Changhua Christian Hospital, Changhua 500, Taiwan.
Tung-Hao ChangDepartment of Radiation Oncology, Changhua Christian Hospital, Changhua 500, Taiwan.
Jhen-Bin LinDepartment of Radiation Oncology, Changhua Christian Hospital, Changhua 500, Taiwan.ORCID 0000-0002-2641-0505
Jin-Ching LinDepartment of Radiation Oncology, Changhua Christian Hospital, Changhua 500, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Definitive concurrent chemoradiation (CCRT) is the standard treatment for cervical esophageal cancer and non-surgical candidates. Initial treatment response affects survival; however, few validated markers are available for prediction. This study evaluated the clinical variables and chemoradiation parameters associated with treatment response. Between May 2010 and April 2016, 86 completed CCRT patients' clinical, dosimetric, and laboratory data at baseline and during treatment were collected. Cox regression analysis assessed the risk factors for overall survival (OS). A receiver operating characteristic curve with Youden's index was chosen to obtain the optimal cut-off value of each parameter. Treatment response was defined per Response Evaluation Criteria in Solid Tumors v.1.1 at the first post-CCRT computed tomography scan. Responders had complete and partial responses; non-responders had stable and progressive diseases. Logistic regression (LR) was used to evaluate the variables associated with responders. The Cox regression model confirmed the presence of responders (

Indexed as

concurrent chemoradiationesophageal cancerradiation dosimetrysurvival outcomes

Identifiers

PMID37760549
PMCPMC10526131

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.