Evidence map›Paper›PMID 37760521›Full record

ArticleCancers2023

Association between Contrast-Enhanced Computed Tomography Radiomic Features, Genomic Alterations and Prognosis in Advanced Lung Adenocarcinoma Patients.

Lisa Rinaldi, Elena Guerini Rocco, Gianluca Spitaleri, Sara Raimondi, Ilaria Attili, Alberto Ranghiero, Giulio Cammarata, Marta Minotti, Giuliana Lo Presti, Francesca De Piano and 12 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Radiogenomics-based prediction ofZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
  10. Prediction of EGFR-TP53 genes co-mutations in patients with lung adenocarcinoma (LUAD) byClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  11. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 4 institutions in 2 countries.

Lisa RinaldiRadiation Research Unit, IEO European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.ORCID 0000-0003-0784-0849
Elena Guerini RoccoDivision of Pathology, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Gianluca SpitaleriDivision of Thoracic Oncology, IEO European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.ORCID 0000-0003-3742-9962
Sara RaimondiDepartment of Experimental Oncology, IEO European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.ORCID 0000-0003-4673-9049
Ilaria AttiliDivision of Thoracic Oncology, IEO European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.ORCID 0000-0003-1333-6622
Alberto RanghieroDivision of Pathology, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Giulio CammarataDepartment of Experimental Oncology, IEO European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Marta MinottiDivision of Radiology, IEO European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Giuliana Lo PrestiDepartment of Experimental Oncology, IEO European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Francesca De PianoDivision of Radiology, IEO European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Federica BellerbaDepartment of Experimental Oncology, IEO European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.ORCID 0000-0002-5956-4340
Gianluigi FunicelliDivision of Radiology, IEO European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Stefania VolpeDepartment of Oncology and Hemato-Oncology, University of Milan, Via Festa del Perdono 7, 20122 Milan, Italy.
Serena MoraData Management Unit, IEO European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Cristiana FodorData Management Unit, IEO European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Cristiano RampinelliDivision of Radiology, IEO European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Massimo BarberisDivision of Pathology, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-0943-4804
Filippo De MarinisDivision of Thoracic Oncology, IEO European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Barbara Alicja Jereczek-FossaDepartment of Oncology and Hemato-Oncology, University of Milan, Via Festa del Perdono 7, 20122 Milan, Italy.
Roberto OrecchiaDivision of Radiology, IEO European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Stefania RizzoClinica di Radiologia EOC, Istituto Imaging della Svizzera Italiana (IIMSI), Via Tesserete 46, 6900 Lugano, Switzerland.ORCID 0000-0002-5151-0866
Francesca BottaMedical Physics Unit, IEO European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Ripamonti · ITUniversity of Milan · ITEuropean Institute of Oncology · ITIstituto Imaging della Svizzera Italiana

Funding

Italian Health Ministry Ricerca Finalizzata GR-2016-02362050
6 · The paper itself

Abstract

Non-invasive methods to assess mutational status, as well as novel prognostic biomarkers, are warranted to foster therapy personalization of patients with advanced non-small cell lung cancer (NSCLC). This study investigated the association of contrast-enhanced Computed Tomography (CT) radiomic features of lung adenocarcinoma lesions, alone or integrated with clinical parameters, with tumor mutational status (

Indexed as

CTgenetic alterationlung cancerradiomicstarget therapy

Identifiers

PMID37760521
PMCPMC10527057
OpenAlexW4386746776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.