Evidence map›Paper›PMID 37760312›Full record

ArticleAnimals : an open access journal from MDPI2023

Three-Dimensional Imaging and Histopathological Features of Third Metacarpal/Tarsal Parasagittal Groove and Proximal Phalanx Sagittal Groove Fissures in Thoroughbred Horses.

Szu-Ting Lin, Alastair K Foote, Nicholas M Bolas, Vanessa G Peter, Rachel Pokora, Hayley Patrick, David R Sargan, Rachel C Murray

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Correlation of 2D Linear and 3D Volumetric Measurement Techniques for Subchondral Bone Sclerosis in the Equine Distal Limb Using Standing Computed Tomography.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Szu-Ting LinDepartment of Veterinary Medicine, University of Cambridge, Madingley Rd., Cambridge CB3 0ES, UK.
Alastair K FooteRossdales Veterinary Surgeons, Cotton End Rd., Exning, Newmarket CB8 7NN, UK.
Nicholas M BolasHallmarq Veterinary Imaging, Unit 5 Bridge Park, Merrow Lane, Guildford GU4 7BF, UK.
Vanessa G PeterRossdales Veterinary Surgeons, Cotton End Rd., Exning, Newmarket CB8 7NN, UK.
Rachel PokoraRossdales Veterinary Surgeons, Cotton End Rd., Exning, Newmarket CB8 7NN, UK.
Hayley PatrickSwayne and Partners Veterinary Surgeons, Western Way, Bury St Edmunds IP33 3SP, UK.
David R SarganDepartment of Veterinary Medicine, University of Cambridge, Madingley Rd., Cambridge CB3 0ES, UK.ORCID 0000-0001-9897-2489
Rachel C MurrayRossdales Veterinary Surgeons, Cotton End Rd., Exning, Newmarket CB8 7NN, UK.

Funding

Horserace Betting Levy Board SPrj53University of Cambridge Charles Slater Fund 2021, School of Biological ScienceUniversity of Cambridge Department of Veterinary MedicineUniversity of Cambridge Friends of the College Fund, Robinson College
6 · The paper itself

Abstract

Fissure in the third metacarpal/tarsal parasagittal groove and proximal phalanx sagittal groove is a potential prodromal pathology of fracture; therefore, early identification and characterisation of fissures using non-invasive imaging could be of clinical value. Thirty-three equine cadaver limbs underwent standing cone-beam (CB) computed tomography (CT), fan-beam (FB) CT, low-field magnetic resonance imaging (MRI), and macro/histo-pathological examination. Imaging diagnoses of fissures were compared to microscopic examination. Imaging features of fissures were described. Histopathological findings were scored and compared between locations with and without fissures on CT. Microscopic examination identified 114/291 locations with fissures. The diagnostic sensitivity and specificity were 88.5% and 61.3% for CBCT, 84.1% and 72.3% for FBCT, and 43.6% and 85.2% for MRI. Four types of imaging features of fissures were characterised on CT: (1) CBCT/FBCT hypoattenuating linear defects, (2) CBCT/FBCT striated hypoattenuated lines, (3) CBCT/FBCT subchondral irregularity, and (4) CBCT striated hypoattenuating lines and FBCT subchondral irregularity. Fissures on MRI appeared as subchondral bone hypo-/hyperintense defects. Microscopic scores of subchondral bone sclerosis, microcracks, and collapse were significantly higher in locations with CT-identified fissures. All imaging modalities were able to identify fissures. Fissures identified on CT were associated with histopathology of fatigue injuries.

Indexed as

computed tomographycone beamfan beamfatigue injuryfissuremagnetic resonance imagingstress fracture

Identifiers

PMID37760312
PMCPMC10525482

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.