Evidence map›Paper›PMID 37760232›Full record

ArticleAnimals : an open access journal from MDPI2023

Unconventional Sites for Diagnosis of Leptospirosis in Bovine Anicteric Fetuses.

Luiza Aymée, Maria Isabel Nogueira Di Azevedo, Luiza Reis, Julia Mendes, Fúlvia de Fátima Almeida de Castro, Filipe Anibal Carvalho-Costa, Guilherme Nunes de Souza, Walter Lilenbaum

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Comparative genomics ofFrontiers in microbiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Luiza AyméeLaboratory of Veterinary Bacteriology, Biomedical Institute, Federal Fluminense University, Niterói 24020-141, RJ, Brazil.ORCID 0000-0002-4041-5775
Maria Isabel Nogueira Di AzevedoLaboratory of Veterinary Bacteriology, Biomedical Institute, Federal Fluminense University, Niterói 24020-141, RJ, Brazil.ORCID 0000-0002-9882-3130
Luiza ReisLaboratory of Veterinary Bacteriology, Biomedical Institute, Federal Fluminense University, Niterói 24020-141, RJ, Brazil.
Julia MendesLaboratory of Veterinary Bacteriology, Biomedical Institute, Federal Fluminense University, Niterói 24020-141, RJ, Brazil.
Fúlvia de Fátima Almeida de CastroCurso de Medicina Veterinária, Federal University of Juiz de Fora, Juiz de Fora 36036-900, MG, Brazil.
Filipe Anibal Carvalho-CostaLaboratory of Epidemiology and Molecular Systematics, Oswaldo Cruz Institute, Rio de Janeiro 21040-900, RJ, Brazil.
Guilherme Nunes de SouzaEmbrapa Dairy Cattle, Juiz de Fora 36038-330, MG, Brazil.ORCID 0000-0003-0049-6133
Walter LilenbaumLaboratory of Veterinary Bacteriology, Biomedical Institute, Federal Fluminense University, Niterói 24020-141, RJ, Brazil.
Universidade Federal Fluminense · BRBrazilian Agricultural Research Corporation · BRFundação Oswaldo Cruz · BRUniversidade Federal de Juiz de Fora · BR

Funding

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro 260003/001162/2020
6 · The paper itself

Abstract

backgroundBovine leptospirosis is an important reproductive disease and abortion is a major sign, leading to economic impacts. Due to its multifactorial etiology, the proper diagnosis of the cause of the abortion is crucial. Necropsy of the fetuses followed by molecular analysis is recommended for diagnosis, and the investigation mainly occurs in the kidneys and liver. This study aimed to analyze unconventional sites for the presence of leptospiral DNA in bovine anicteric aborted fetuses.

methodsFive fetuses of the same herd were received for necropsy and diagnosis. Conventional

resultsThe herd presented seroreactive animals (11/30, 36.6%), all against the Sejroe serogroup, with titers between 200 and 1600. In necropsy, four fetuses showed hemorrhagic and anicteric lesions, while one fetus had no macroscopic lesions. Regarding molecular analysis, all the fetuses were positive in

conclusionsIn order to improve the diagnosis of leptospirosis in cows, it is recommended to perform a comprehensive analysis of the samples, beyond the kidneys and liver. Thus, we highly encourage testing multiple organs by PCR to investigate abortions suspected of bovine leptospirosis, particularly in anicteric fetuses.

Indexed as

abomasal fluidabortioncattleleptospiral infectionlipL32molecular analysisnecropsy

Identifiers

PMID37760232
PMCPMC10525537
OpenAlexW4386475726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.