Evidence map›Paper›PMID 37760219›Full record

ArticleAnimals : an open access journal from MDPI2023

Genomic Epidemiology and Evolution of Fowl Adenovirus 1.

Szilvia Jakab, Krisztina Bali, Zalán Homonnay, Eszter Kaszab, Katalin Ihász, Enikő Fehér, Tamás Mató, István Kiss, Vilmos Palya, Krisztián Bányai

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Szilvia JakabVeterinary Medical Research Institute, Hungária krt. 21, H-1143 Budapest, Hungary.ORCID 0009-0005-8435-5507
Krisztina BaliVeterinary Medical Research Institute, Hungária krt. 21, H-1143 Budapest, Hungary.ORCID 0000-0002-6906-0226
Zalán HomonnayCeva-Phylaxia Ltd., Szállás u. 5, H-1107 Budapest, Hungary.ORCID 0000-0003-2473-1775
Eszter KaszabVeterinary Medical Research Institute, Hungária krt. 21, H-1143 Budapest, Hungary.ORCID 0000-0002-5750-1872
Katalin IhászVeterinary Medical Research Institute, Hungária krt. 21, H-1143 Budapest, Hungary.
Enikő FehérVeterinary Medical Research Institute, Hungária krt. 21, H-1143 Budapest, Hungary.ORCID 0000-0001-7778-9116
Tamás MatóCeva-Phylaxia Ltd., Szállás u. 5, H-1107 Budapest, Hungary.
István KissCeva-Phylaxia Ltd., Szállás u. 5, H-1107 Budapest, Hungary.ORCID 0000-0001-7839-4415
Vilmos PalyaCeva-Phylaxia Ltd., Szállás u. 5, H-1107 Budapest, Hungary.ORCID 0000-0003-3319-9995
Krisztián BányaiVeterinary Medical Research Institute, Hungária krt. 21, H-1143 Budapest, Hungary.
National Food Chain Safety Office · HUHUN-REN Veterinary Medical Research Institute · HU

Funding

Hungarian Scientific Research Fund K120201National Laboratory for Infectious Animal Diseases, Antimicrobial Resistance, Veterinary Public Health, and Food Chain Safety RRF-2.3.1-21-2022-00001National Research, Development and Innovation Fund ÚNKP-22-4-I-ÁTE-3
6 · The paper itself

Abstract

Fowl adenovirus 1 (FAdV-1) is the main cause of gizzard erosion in chickens. Whole genome sequencing and sequence analyses of 32 FAdV-1 strains from a global collection provided evidence that multiple recombination events have occurred along the entire genome. In gene-wise phylogenies, only the adenoviral pol gene formed a tree topology that corresponded to whole genome-based phylogeny. Virus genetic features that were clearly connected to gizzard erosion were not identified in our analyses. However, some genome variants tended to be more frequently identified from birds with gizzard erosion and strains isolated from healthy birds or birds with non-specific pathologies tended to form common clusters in multiple gene phylogenies. Our data show that the genetic diversity is greater, and the evolutionary mechanisms are more complex within FAdV-1 than previously thought. The implications of these findings for viral pathogenesis and epidemiology await further investigation.

Indexed as

Fowl adenovirus Agenotypinggizzard erosionphylogenetic analysisrecombination

Identifiers

PMID37760219
PMCPMC10525556
OpenAlexW4386457146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.