Evidence map›Paper›PMID 37760146›Full record

ArticleBioengineering (Basel, Switzerland)2023

MRI-Based Deep Learning Method for Classification of IDH Mutation Status.

Chandan Ganesh Bangalore Yogananda, Benjamin C Wagner, Nghi C D Truong, James M Holcomb, Divya D Reddy, Niloufar Saadat, Kimmo J Hatanpaa, Toral R Patel, Baowei Fei, Matthew D Lee and 5 more

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Review
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  9. Article
  10. Biogenesis and functional implications of extracellular vesicles in cancer metastasis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  11. Data Harmonization with StyleTransfer-GANs: Enhancing Non-Invasive IDH Classification in Brain Tumors.Proceedings of SPIE--the International Society for Optical Engineering · 2025
    Article
  12. Article
  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Chandan Ganesh Bangalore YoganandaDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Benjamin C WagnerDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0003-2835-986X
Nghi C D TruongDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
James M HolcombDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Divya D ReddyDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Niloufar SaadatDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Kimmo J HatanpaaDepartment of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Toral R PatelDepartment of Neurological Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Baowei FeiDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Matthew D LeeDepartment of Radiology, NYU Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0001-8816-1076
Rajan JainDepartment of Radiology, NYU Grossman School of Medicine, New York, NY 10016, USA.
Richard J BruceDepartment of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53726, USA.
Marco C PinhoDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Ananth J MadhuranthakamDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Joseph A MaldjianDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Funding

Quantitative Non-Contrast Perfusion using Arterial Spin Labeling for Assessment of Cancer Therapy ResponseU01CA207091 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI MADHURANTHAKAM, ANANTH J, MALDJIAN, JOSEPH A · 2017 to 2022
$3.1M
Virtual Biopsy with Tissue-level Accuracy in GliomaR01CA260705 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI MALDJIAN, JOSEPH A · 2021 to 2025
$3.1M
Training Clinician Scientists as Outstanding Clinicians and Imaging ScientistsT32EB028093 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI ROBERT F MATTREY, Takeshi Yokoo · 2019 to 2026
$1.5M
NCI NIH HHS R01 CA260705NCI NIH HHS U01 CA207091NIBIB NIH HHS T32 EB028093
6 · The paper itself

Abstract

Isocitrate dehydrogenase (IDH) mutation status has emerged as an important prognostic marker in gliomas. This study sought to develop deep learning networks for non-invasive IDH classification using T2w MR images while comparing their performance to a multi-contrast network. Methods: Multi-contrast brain tumor MRI and genomic data were obtained from The Cancer Imaging Archive (TCIA) and The Erasmus Glioma Database (EGD). Two separate 2D networks were developed using

Indexed as

brain tumorCNNdeep learninggliomasIDHMRInnU-NetU-net

Identifiers

PMID37760146
PMCPMC10525372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.