Evidence map›Paper›PMID 37760050›Full record

ReviewAntioxidants (Basel, Switzerland)2023

Insights on the Multifaceted Roles of Wild-Type and Mutated Superoxide Dismutase 1 in Amyotrophic Lateral Sclerosis Pathogenesis.

Valentina Rubino, Giuliana La Rosa, Luca Pipicelli, Flavia Carriero, Simona Damiano, Mariarosaria Santillo, Giuseppe Terrazzano, Giuseppina Ruggiero, Paolo Mondola

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Valentina RubinoDipartimento di Scienze Mediche Traslazionali, Università di Napoli "Federico II", Via Pansini 5, 80131 Naples, Italy.ORCID 0000-0002-5646-2795
Giuliana La RosaDipartimento di Medicina Clinica e Chirurgia, Università di Napoli "Federico II", Via Pansini 5, 80131 Naples, Italy.
Luca PipicelliDipartimento di Medicina Clinica e Chirurgia, Università di Napoli "Federico II", Via Pansini 5, 80131 Naples, Italy.
Flavia CarrieroDipartimento di Scienze, Università della Basilicata, Via dell'Ateneo Lucano 10, 85100 Potenza, Italy.
Simona DamianoDipartimento di Medicina Clinica e Chirurgia, Università di Napoli "Federico II", Via Pansini 5, 80131 Naples, Italy.
Mariarosaria SantilloDipartimento di Medicina Clinica e Chirurgia, Università di Napoli "Federico II", Via Pansini 5, 80131 Naples, Italy.ORCID 0000-0003-1260-8980
Giuseppe TerrazzanoDipartimento di Scienze, Università della Basilicata, Via dell'Ateneo Lucano 10, 85100 Potenza, Italy.ORCID 0000-0003-3556-6891
Giuseppina RuggieroDipartimento di Scienze Mediche Traslazionali, Università di Napoli "Federico II", Via Pansini 5, 80131 Naples, Italy.ORCID 0000-0002-8975-6001
Paolo MondolaDipartimento di Medicina Clinica e Chirurgia, Università di Napoli "Federico II", Via Pansini 5, 80131 Naples, Italy.
University of Naples Federico II · ITUniversity of Basilicata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyotrophic Lateral Sclerosis (ALS) is a progressive motor neurodegenerative disease. Cell damage in ALS is the result of many different, largely unknown, pathogenetic mechanisms. Astrocytes and microglial cells play a critical role also for their ability to enhance a deranged inflammatory response. Excitotoxicity, due to excessive glutamate levels and increased intracellular Ca

Indexed as

Amyotrophic Lateral Sclerosis (ALS)excitotoxicityimmune response regulationintracellular signalingneurodegenerationSuperoxide Dismutase 1 (SOD1)

Identifiers

PMID37760050
PMCPMC10525763
OpenAlexW4386601496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.