Evidence map›Paper›PMID 37760036›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Antioxidant Interactions between Citrus Fruit Carotenoids and Ascorbic Acid in New Models of Animal Cell Membranes.

Marcelo P Barros, Jaime Zacarías-Garcia, Florencia Rey, Lorenzo Zacarías, María J Rodrigo

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Marcelo P BarrosFood Biotechnology Department, Institute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Catedrático Agustín Escardino 7, Paterna, 46980 Valencia, Spain.ORCID 0000-0003-3565-8331
Jaime Zacarías-GarciaFood Biotechnology Department, Institute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Catedrático Agustín Escardino 7, Paterna, 46980 Valencia, Spain.
Florencia ReyFood Biotechnology Department, Institute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Catedrático Agustín Escardino 7, Paterna, 46980 Valencia, Spain.
Lorenzo ZacaríasFood Biotechnology Department, Institute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Catedrático Agustín Escardino 7, Paterna, 46980 Valencia, Spain.ORCID 0000-0003-3982-8860
María J RodrigoFood Biotechnology Department, Institute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Catedrático Agustín Escardino 7, Paterna, 46980 Valencia, Spain.ORCID 0000-0003-2668-0684
Consejo Superior de Investigaciones Científicas · ES

Funding

Fundación Severo Ochoa CEX2021-001189-S/ MCIN/AEI / 10.13039/501100011033National Council for Scientific and Technological Development 311839/2021-5São Paulo Research Foundation 2017/06032-2
6 · The paper itself

Abstract

The regular consumption of citrus fruits by humans has been associated with lower incidence of chronic-degenerative diseases, especially those mediated by free radicals. Most of the health-promoting properties of citrus fruits derive from their antioxidant content of carotenoids and ascorbic acid (ASC). In the current work we have investigated the scavenging (against hydroxyl radical) and quenching capacities (against singlet oxygen) of four different carotenoid extracts of citrus fruits in the presence or absence of ASC (μM range) in organic solvent, aqueous solution, micelles and in an innovative biomimicking liposomal system of animal cell membrane (AML). The fruits of four varieties of citrus were selected for their distinctive carotenoid composition (liquid chromatography characterization): 'Nadorcott' mandarin and the sweet oranges 'Valencia late', 'Ruby Valencia' and 'Pinalate' mutant. The quenching activity of citrus carotenoids strongly depended on the biological assemblage: freely diffusible in organic solvent, 'Ruby Valencia' carotenoids (containing lycopene) showed the highest quenching activity, whereas 'Nadorcott' mandarin extracts, rich in β-cryptoxanthin, prevailed in micellar systems. Interestingly, the addition of 10 μM ASC significantly increased the quenching activity of all citrus extracts in micelles: 'Valencia' orange (+53%), 'Pinalate' (+87%), 'Ruby' (4-fold higher) and 'Nadorcott' mandarins (+20%). Accurate C

Indexed as

foodfree radicalslipid peroxidationmicronutrientnutritionoxidative stresssinglet oxygenvitamin

Identifiers

PMID37760036
PMCPMC10525925
OpenAlexW4386498561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.