Evidence map›Paper›PMID 37759909›Full record

ArticleBrain sciences2023

Analysis of Serum Markers of Perioperative Brain Injury and Inflammation Associated with Endovascular Treatment of Intracranial Aneurysms: A Preliminary Study.

Mikołaj Zimny, Piotr Paździora, Damian Kocur, Bartłomiej Błaszczyk, Daria Gendosz de Carrillo, Jan Baron, Halina Jędrzejowska-Szypułka, Adam Rudnik

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In one paragraph

Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 71% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mikołaj ZimnyDepartment of Neurosurgery, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.ORCID 0000-0002-2166-6392
Piotr PaździoraDepartment of Neurosurgery, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.
Damian KocurDepartment of Neurosurgery, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.
Bartłomiej BłaszczykDepartment of Neurosurgery, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.
Daria Gendosz de CarrilloDepartment of Physiology, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.ORCID 0000-0001-5090-8365
Jan BaronDepartment of Radiodiagnostics, Interventional Radiology and Nuclear Medicine, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.
Halina Jędrzejowska-SzypułkaDepartment of Physiology, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.
Adam RudnikDepartment of Neurosurgery, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.
Medical University of Silesia · PL

Funding

Medical University of Silesia PCN-1-139/N/0/K
6 · The paper itself

Abstract

Embolization is the preferred method for treating intracranial aneurysms due to its less invasive nature. However, recent findings suggest that even uncomplicated embolization may cause structural damage to the brain through ischemic or inflammatory mechanisms. This study aimed to find possible biomarkers of brain injury and inflammation in patients suffering from intracranial aneurysms who underwent endovascular treatment by measuring serological markers indicating brain damage. The study involved 26 patients who underwent uncomplicated intravascular stenting for unruptured intracranial aneurysms between January 2020 and December 2021. Blood samples were collected before the procedure, at 6-12 h, and at 24 h after the procedure. The following protein biomarkers levels were tested with ELISA: S100B, hNSE, TNF, hsCRP, FABP7, NFL, and GP39. Statistical analysis of the results revealed significant increases in serum levels for the four biomarkers: FABP7-before 0.25 (ng/mL) vs. 6-12 h 0.26 (

Indexed as

brain injuryendovascular embolizationinflammationintracranial aneurysmsserum markers

Identifiers

PMID37759909
PMCPMC10526942
OpenAlexW4386601387

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.