Metabolite Variations in the Hippocampus and Corpus Callosum of Patients with Mild Cognitive Impairment Using Magnetic Resonance Spectroscopy with Three-Dimensional Chemical Shift Images.

Yen-Lon Kau, I-Hung Lin, Chi-Long Juang, Chao-Kai Chang, Wen-Hsiang Ho, Hsiao-Chuan Wen

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Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.5field-weighted citation impact, top 33% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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0 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yen-Lon KauDepartment of Medical Imaging, Camillian St. Mary's Hospital, Luodong, Yilan 265502, Taiwan.

I-Hung LinNobel Eye Institute, Taipei 100008, Taiwan.ORCID 0000-0003-4268-2540

Chi-Long JuangDepartment of Medical Imaging and Radiological Sciences, Yuanpei University, Hsinchu 30015, Taiwan.

Chao-Kai ChangNobel Eye Institute, Taipei 100008, Taiwan.

Wen-Hsiang HoDepartment of Medical Imaging, Camillian St. Mary's Hospital, Luodong, Yilan 265502, Taiwan.

Hsiao-Chuan WenDepartment of Pet Healthcare, Yuanpei University, Hsinchu 300, Taiwan.

Yuanpei University · TWNational Taiwan University · TWSaint Mary's Hospital Luodong · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study compared the metabolites in the brain regions of hippocampus and corpus callosum between patients with mild cognitive impairment (MCI) and healthy controls using no-radiation and high-sensitivity magnetic resonance spectroscopy (MRS) with three-dimensional chemical shift images (3D-CSI). Twenty volunteers (seven patients with MCI and 13 healthy controls) aged 50-71 years were recruited for this prospective study. MRS with 3D-CSI images of a variety of metabolites was collected from the hippocampus and corpus callosum. Sex and weight showed no significant differences between the two groups. The metabolite levels in the hippocampus and corpus callosum of the MCI group were generally lower than in those of the healthy group, especially for creatine (

Indexed as

corpus callosumhippocampal gyrusmagnetic resonance imagingmagnetic resonance spectroscopymild cognitive impairment

Identifiers

PMID37759845

DOI10.3390/brainsci13091244

PMCPMC10526271

OpenAlexW4386222281

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.