Evidence map›Paper›PMID 37759820›Full record

ArticleBiomolecules2023

Conservation of Glutathione Transferase mRNA and Protein Sequences Similar to Human and Horse Alpha Class GST A3-3 across Dog, Goat, and Opossum Species.

Shawna M Hubert, Paul B Samollow, Helena Lindström, Bengt Mannervik, Nancy H Ing

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Glutathione Transferases as Efficient Ketosteroid Isomerases.Frontiers in molecular biosciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Shawna M HubertDepartment of Animal Science, Texas A&M AgriLife Research, Texas A&M University, College Station, TX 77843-2471, USA.ORCID 0000-0002-7907-9609
Paul B SamollowDepartment of Veterinary Integrative Biosciences, School of Veterinary Medicine and Biosciences, Texas A&M University, College Station, TX 77843-2471, USA.
Helena LindströmDepartment of Biochemistry and Biophysics, Arrhenius Laboratories, Stockholm University, SE-10691 Stockholm, Sweden.
Bengt MannervikDepartment of Biochemistry and Biophysics, Arrhenius Laboratories, Stockholm University, SE-10691 Stockholm, Sweden.ORCID 0000-0002-6416-064X
Nancy H IngDepartment of Animal Science, Texas A&M AgriLife Research, Texas A&M University, College Station, TX 77843-2471, USA.ORCID 0000-0002-5601-6971
Stockholm University · SETexas A&M University · USThe University of Texas MD Anderson Cancer Center · US

Funding

Resource for Biocomputing Visualization and InformaticsP41GM103311 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2012 to 2017
$8.2M
NIGMS NIH HHS P41 GM103311
6 · The paper itself

Abstract

The glutathione transferase A3-3 (GST A3-3) homodimeric enzyme is the most efficient enzyme that catalyzes isomerization of the precursors of testosterone, estradiol, and progesterone in the gonads of humans and horses. However, the presence of GST A3-3 orthologs with equally high ketosteroid isomerase activity has not been verified in other mammalian species, even though pig and cattle homologs have been cloned and studied. Identifying

Indexed as

Glutathione TransferaseGoatsAnimalsCattleDogsHorsesHumansIsomerasesKetosteroidsOpossumsRNA, MessengerSteroidsSwineGlutathione TransferaseIsomerasesKetosteroidsRNA, MessengerSteroidsestrogenglutathione transferase A3-3 (GST A3-3)progesteronesteroidogenesistestestestosterone

Identifiers

PMID37759820
PMCPMC10526480
OpenAlexW4386933950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.