Evidence map›Paper›PMID 37759791›Full record

ArticleBiomolecules2023

Transformer-Based Multi-Modal Data Fusion Method for COPD Classification and Physiological and Biochemical Indicators Identification.

Weidong Xie, Yushan Fang, Guicheng Yang, Kun Yu, Wei Li

Abstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Prognostic Value of Biomarkers in Chronic Obstructive Pulmonary Disease: A Comprehensive Review.International journal of chronic obstructive pulmonary disease · 2025
    Review
  8. Lobar Lung Density Embeddings with a Transformer encoder (LobTe) to predict emphysema progression in COPD.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2024
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Weidong XieSchool of Computer Science and Engineering, Northeastern University, Hunnan District, Shenyang 110169, China.ORCID 0000-0003-1930-4509
Yushan FangSchool of Computer Science and Engineering, Northeastern University, Hunnan District, Shenyang 110169, China.
Guicheng YangSchool of Computer Science and Engineering, Northeastern University, Hunnan District, Shenyang 110169, China.
Kun YuCollege of Medicine and Bioinformation Engineering, Northeastern University, Hunnan District, Shenyang 110169, China.
Wei LiSchool of Computer Science and Engineering, Northeastern University, Hunnan District, Shenyang 110169, China.

Funding

National Frontiers Science Center for Industrial Intelligence and Systems Optimization, Shenyang 110819, the 111 Project B16009National Key Research and Development Program of China 2021YFC2701003Natural Science Foundation of Liaoning Province under grant 2022JH2/101300075
6 · The paper itself

Abstract

As the number of modalities in biomedical data continues to increase, the significance of multi-modal data becomes evident in capturing complex relationships between biological processes, thereby complementing disease classification. However, the current multi-modal fusion methods for biomedical data require more effective exploitation of intra- and inter-modal interactions, and the application of powerful fusion methods to biomedical data is relatively rare. In this paper, we propose a novel multi-modal data fusion method that addresses these limitations. Our proposed method utilizes a graph neural network and a 3D convolutional network to identify intra-modal relationships. By doing so, we can extract meaningful features from each modality, preserving crucial information. To fuse information from different modalities, we employ the Low-rank Multi-modal Fusion method, which effectively integrates multiple modalities while reducing noise and redundancy. Additionally, our method incorporates the Cross-modal Transformer to automatically learn relationships between different modalities, facilitating enhanced information exchange and representation. We validate the effectiveness of our proposed method using lung CT imaging data and physiological and biochemical data obtained from patients diagnosed with Chronic Obstructive Pulmonary Disease (COPD). Our method demonstrates superior performance compared to various fusion methods and their variants in terms of disease classification accuracy.

Indexed as

Pulmonary Disease, Chronic ObstructiveAlgorithmsHumansLungNeural Networks, ComputerTomography, X-Ray ComputedCOPDcross-modal transformerlow-rank multi-modal fusionmulti-modal fusion

Identifiers

PMID37759791
PMCPMC10527317

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.