Evidence map›Paper›PMID 37759766›Full record

ArticleBiomolecules2023

Structure-Activity Relationships of Low Molecular Weight Alginate Oligosaccharide Therapy against

Manon F Pritchard, Lydia C Powell, Jennifer Y M Adams, Georgina Menzies, Saira Khan, Anne Tøndervik, Håvard Sletta, Olav Aarstad, Gudmund Skjåk-Bræk, Stephen McKenna and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Manon F PritchardAdvanced Therapies Group, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
Lydia C PowellAdvanced Therapies Group, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
Jennifer Y M AdamsAdvanced Therapies Group, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
Georgina MenziesSchool of Biosciences, Cardiff University, Cardiff CF10 3AX, UK.ORCID 0000-0002-6600-6507
Saira KhanAdvanced Therapies Group, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
Anne TøndervikDepartment of Bioprocess Technology, SINTEF Materials and Chemistry, N-7465 Trondheim, Norway.
Håvard SlettaDepartment of Bioprocess Technology, SINTEF Materials and Chemistry, N-7465 Trondheim, Norway.
Olav AarstadDepartment of Biotechnology, Norwegian University of Science and Technology, N-7491 Trondheim, Norway.
Gudmund Skjåk-BrækDepartment of Biotechnology, Norwegian University of Science and Technology, N-7491 Trondheim, Norway.
Stephen McKennaAdvanced Therapies Group, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
Niklaas J BuurmaPhysical Organic Chemistry Centre, School of Chemistry, Cardiff University, Cardiff CF10 3AT, UK.ORCID 0000-0003-0260-5057
Damian J J FarnellAdvanced Therapies Group, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.ORCID 0000-0003-0662-1927
Philip D RyeAlgiPharma AS, Industriveien 33, N-1337 Sandvika, Norway.ORCID 0000-0001-7762-3300
Katja E HillAdvanced Therapies Group, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.ORCID 0000-0002-8590-0117
David W ThomasAdvanced Therapies Group, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.ORCID 0000-0001-7319-5820
Cardiff University · GBNorwegian University of Science and Technology · NOSINTEF · NOAlgiPharma (Norway) · NOSwansea University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low molecular weight alginate oligosaccharides have been shown to exhibit anti-microbial activity against a range of multi-drug resistant bacteria, including

Indexed as

AlginatesPseudomonas aeruginosaAnti-Bacterial AgentsMolecular WeightStructure-Activity RelationshipAlginatesAnti-Bacterial Agentsalginate oligosaccharidebiofilmcalciumguluronic acidmannuronic acidPseudomonas aeruginosa

Identifiers

PMID37759766
PMCPMC10527064
OpenAlexW4386601276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.