Evidence map›Paper›PMID 37759708›Full record

ArticleBiomolecules2023

Transition Mutations in the hTERT Promoter Are Unrelated to Potential i-motif Formation in the C-Rich Strand.

James W Conrad, Mark L Sowers, Dianne Y Yap, Ellie Cherryhomes, B Montgomery Pettitt, Kamil Khanipov, Lawrence C Sowers

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
  3. Position-Dependent Effects of AP Sites Within anInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

James W ConradDepartment of Pharmacology and Toxicology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Mark L SowersDepartment of Pharmacology and Toxicology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Dianne Y YapDepartment of Pharmacology and Toxicology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Ellie CherryhomesDepartment of Pharmacology and Toxicology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
B Montgomery PettittDepartment of Pharmacology and Toxicology, The University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0000-0003-4902-3046
Kamil KhanipovDepartment of Pharmacology and Toxicology, The University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0000-0002-3881-737X
Lawrence C SowersDepartment of Pharmacology and Toxicology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
The University of Texas Medical Branch at Galveston · US

Funding

Cytosine Deamination Adducts and Cancer EtiologyR01CA228085 · NCI · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SOWERS, LAWRENCE C · 2019 to 2023
$2.1M
NCI NIH HHS R01 CA228085NIH HHS R01CA228085
6 · The paper itself

Abstract

Increased expression of the human telomere reverse transcriptase (hTERT) in tumors promotes tumor cell survival and diminishes the survival of patients. Cytosine-to-thymine (C-to-T) transition mutations (C250T or C228T) in the

Indexed as

CytosineTelomeraseBinding SitesCell SurvivalDNA, ComplementaryHumansMutationCytosineDNA, ComplementaryTelomerasecytosine deaminationquadruplextelomerasetelomeretransition mutation

Identifiers

PMID37759708
PMCPMC10526324
OpenAlexW4386169088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.