Evidence map›Paper›PMID 37759666›Full record

ReviewBiology2023

From Alpha to Omicron: How Different Variants of Concern of the SARS-Coronavirus-2 Impacted the World.

Mickensone Andre, Lee-Seng Lau, Marissa D Pokharel, Julian Ramelow, Florida Owens, Joseph Souchak, Juliet Akkaoui, Evan Ales, Harry Brown, Rajib Shil and 6 more

Abstract readReview
In one paragraph

Review in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed.

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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Mickensone AndreHerbert Wertheim College of Medicine, Biomedical Sciences Program Florida International University, Miami, FL 33199, USA.
Lee-Seng LauHerbert Wertheim College of Medicine, Biomedical Sciences Program Florida International University, Miami, FL 33199, USA.
Marissa D PokharelHerbert Wertheim College of Medicine, Biomedical Sciences Program Florida International University, Miami, FL 33199, USA.ORCID 0000-0002-6566-1817
Julian RamelowHerbert Wertheim College of Medicine, Biomedical Sciences Program Florida International University, Miami, FL 33199, USA.ORCID 0000-0002-7465-4512
Florida OwensHerbert Wertheim College of Medicine, Biomedical Sciences Program Florida International University, Miami, FL 33199, USA.
Joseph SouchakHerbert Wertheim College of Medicine, Biomedical Sciences Program Florida International University, Miami, FL 33199, USA.
Juliet AkkaouiHerbert Wertheim College of Medicine, Biomedical Sciences Program Florida International University, Miami, FL 33199, USA.ORCID 0000-0003-1716-4928
Evan AlesHerbert Wertheim College of Medicine, Biomedical Sciences Program Florida International University, Miami, FL 33199, USA.
Harry BrownHerbert Wertheim College of Medicine, Biomedical Sciences Program Florida International University, Miami, FL 33199, USA.
Rajib ShilHerbert Wertheim College of Medicine, Biomedical Sciences Program Florida International University, Miami, FL 33199, USA.
Valeria NazaireHerbert Wertheim College of Medicine, Biomedical Sciences Program Florida International University, Miami, FL 33199, USA.
Marko ManevskiHerbert Wertheim College of Medicine, Biomedical Sciences Program Florida International University, Miami, FL 33199, USA.
Ngozi P PaulHerbert Wertheim College of Medicine, Biomedical Sciences Program Florida International University, Miami, FL 33199, USA.ORCID 0000-0003-0423-195X
Maria Esteban-LopezHerbert Wertheim College of Medicine, Biomedical Sciences Program Florida International University, Miami, FL 33199, USA.
Yasemin CeyhanHerbert Wertheim College of Medicine, Biomedical Sciences Program Florida International University, Miami, FL 33199, USA.
Nazira El-HageHerbert Wertheim College of Medicine, Biomedical Sciences Program Florida International University, Miami, FL 33199, USA.

Funding

Transdisciplinary Training in Biomolecular and Biomedical SciencesT32GM132054 · NIGMS · FLORIDA INTERNATIONAL UNIVERSITY · PI DEGENNARO, MATTHEW, TSE-DINH, YUK-CHING · 2019 to 2023
$1.6M
NIGMS NIH HHS T32 GM132054
6 · The paper itself

Abstract

SARS-CoV-2, the virus that causes COVID-19, is prone to mutations and the generation of genetic variants. Since its first outbreak in 2019, SARS-CoV-2 has continually evolved, resulting in the emergence of several lineages and variants of concern (VOC) that have gained more efficient transmission, severity, and immune evasion properties. The World Health Organization has given these variants names according to the letters of the Greek Alphabet, starting with the Alpha (B.1.1.7) variant, which emerged in 2020, followed by the Beta (B.1.351), Gamma (P.1), Delta (B.1.617.2), and Omicron (B.1.1.529) variants. This review explores the genetic variation among different VOCs of SARS-CoV-2 and how the emergence of variants made a global impact on the pandemic.

Indexed as

ACE2 receptorcoronavirusgenetic variationvariants of concern

Identifiers

PMID37759666
PMCPMC10525159

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.