Evidence map›Paper›PMID 37759659›Full record

ArticleBiology2023

Effects of Diet Consistency on Rat Maxillary and Mandibular Growth within Three Generations-A Longitudinal CBCT Study.

Ioannis A Tsolakis, Christos Verikokos, Despoina Perrea, Paula Perlea, Konstantina-Eleni Alexiou, Zafeiroula Yfanti, Ioannis Lyros, Maria Georgaki, Erofili Papadopoulou, Apostolos I Tsolakis

Open access · goldAbstract read
In one paragraph

Article in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. The Effect of Diabetes Mellitus on Mandibular Growth.Turkish journal of orthodontics · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Ioannis A TsolakisDepartment of Orthodontics, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-5435-4889
Christos VerikokosSecond Department of Surgery, "Laikon Hospital", School of Medicine, National and Kapodistrian University of Athens, 15772 Athens, Greece.
Despoina PerreaLaboratory of Experimental Surgery and Surgical Research, School of Medicine, National and Kapodistrian University of Athens, 15772 Athens, Greece.
Paula PerleaDepartment of Endodontics, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-1466-820X
Konstantina-Eleni AlexiouDepartment of Oral Diagnosis & Radiology, School of Dentistry, National and Kapodistrian University of Athens, 10679 Athens, Greece.ORCID 0000-0001-6922-895X
Zafeiroula YfantiDepartment of Oral Diagnosis & Radiology, School of Dentistry, National and Kapodistrian University of Athens, 10679 Athens, Greece.
Ioannis LyrosDepartment of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, 15772 Athens, Greece.ORCID 0000-0002-5897-6116
Maria GeorgakiDepartment of Oral Medicine & Pathology and Hospital Dentistry, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-0734-8857
Erofili PapadopoulouDepartment of Oral Medicine & Pathology and Hospital Dentistry, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Apostolos I TsolakisDepartment of Orthodontics, Case Western Reserve University School of Dental Medicine, Cleveland, OH 44106-7342, USA.ORCID 0000-0003-3019-5438
National and Kapodistrian University of Athens · GRAristotle University of Thessaloniki · GRCarol Davila University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this study, wistar rats were used to examine the impact of diet consistency on maxillary and mandibular growth over three generations.

methodsIn this investigation, a breeding sample of 60 female and 8 male wistar rats was used. Measuring was only performed on female animals. The first generation's primary breeding sample consisted of 20 female wistar rats that were 30 days old and 4 male rats that were also 30 days old; two subsequent generations were created from these animals. At the age of 100 days, CBCTs were collected of all male rats. Twenty-eight craniofacial landmarks were selected for the linear measurements on stl format extracted from the DICOM files. A Bonferroni test was performed for the statistical analysis.

resultsMeans of measurements of all soft diet groups compared to corresponding measurements of the hard diet groups were significantly different. According to linear measurements, there was statistical difference on the maxillary measurements between the soft diet groups of the first and third generation, while the rest did not appear to have any statistical difference. There was significant difference for the mandibular dimensions only when the first generation soft diet group was compared with the third generation soft diet group.

conclusionsFood consistency has a significant impact on the growth and development of the maxilla and mandible. Soft diet habits may result in retrognathic mandible, and narrower maxilla.

Indexed as

condylar processgrowthhard dietmandiblemaxillasoft diet

Identifiers

PMID37759659
PMCPMC10526017
OpenAlexW4386933989

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.