Evidence map›Paper›PMID 37759586›Full record

ArticleBiology2023

Discovery of

Ning Li, Yan-Jie Li, Xiao-Juan Guo, Shao-Hui Wu, Wei-Feng Jiang, Dao-Liang Zhang, Kun-Wei Wang, Li Li, Yu-Min Sun, Ying-Jia Xu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 citations in OpenAlex.

  1. NovelBiomedicines · 2026
    Article
  2. Discovery ofDiagnostics (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Discovery ofDiagnostics (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Chromosomal Location and Identification ofDiagnostics (Basel, Switzerland) · 2025
    Article
  7. Identification and Functional Investigation ofDiagnostics (Basel, Switzerland) · 2024
    Article
  8. Discovery and functional investigation ofAmerican journal of translational research · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Ning LiDepartment of Cardiology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Yan-Jie LiDepartment of Cardiology, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, China.
Xiao-Juan GuoDepartment of Cardiology, Shanghai Fifth People's Hospital, Fudan University, Shanghai 200240, China.
Shao-Hui WuDepartment of Cardiology, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, China.
Wei-Feng JiangDepartment of Cardiology, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, China.
Dao-Liang ZhangCardiac Arrhythmia Center, Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen 518057, China.
Kun-Wei WangDepartment of Cardiology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China.
Li LiKey Laboratory of Arrhythmias, Ministry of Education of China, Tongji University School of Medicine, Shanghai 200092, China.
Yu-Min SunDepartment of Cardiology, Shanghai Jing'an District Central Hospital, Fudan University, Shanghai 200040, China.
Ying-Jia XuDepartment of Cardiology, Shanghai Fifth People's Hospital, Fudan University, Shanghai 200240, China.
Yi-Qing YangDepartment of Cardiology, Shanghai Fifth People's Hospital, Fudan University, Shanghai 200240, China.ORCID 0000-0003-0291-8395
Xing-Biao QiuDepartment of Cardiology, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, China.
Fudan University · CNShanghai Jiao Tong University · CNTongji University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNShanghai University of Traditional Chinese Medicine · CN

Funding

The Basic Research Project of Shanghai, China 20JC1418800The Experimental Animal Project of Shanghai, China 201409004400The National Natural Science Foundation of China 82070331The Natural Science Foundation of Shanghai, China 22ZR1454100The Science and Technology Innovation Action Star Project of Shanghai, China 22YF1443000The "Xinglin Scholars" Discipline Talent Research Promotion Project of Chengdu University of Traditional Chinese Medicine, Sichuan, China YYZX2022166
6 · The paper itself

Abstract

Atrial fibrillation (AF), the most prevalent type of sustained cardiac dysrhythmia globally, confers strikingly enhanced risks for cognitive dysfunction, stroke, chronic cardiac failure, and sudden cardiovascular demise. Aggregating studies underscore the crucial roles of inherited determinants in the occurrence and perpetuation of AF. However, due to conspicuous genetic heterogeneity, the inherited defects accounting for AF remain largely indefinite. Here, via whole-genome genotyping with genetic markers and a linkage assay in a family suffering from AF, a new AF-causative locus was located at human chromosome 7p14.2-p14.3, a ~4.89 cM (~4.43-Mb) interval between the markers D7S526 and D7S2250. An exome-wide sequencing assay unveiled that, at the defined locus, the mutation in the

Indexed as

atrial fibrillationbiological assaycardiac arrhythmialinkage analysismedical geneticsmolecular biologyTBX20transcriptional regulation

Identifiers

PMID37759586
PMCPMC10525918
OpenAlexW4386303326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.