Evidence map›Paper›PMID 37759504›Full record

ArticleCells2023

Complement C3 Reduces Apoptosis via Interaction with the Intrinsic Apoptotic Pathway.

Zhou Fang, Haekyung Lee, Junying Liu, Karen A Wong, Lewis M Brown, Xiang Li, Alus M Xiaoli, Fajun Yang, Ming Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Zhou FangDepartments of Anesthesiology, SUNY Downstate Health Science University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
Haekyung LeeDepartments of Anesthesiology, SUNY Downstate Health Science University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
Junying LiuDepartments of Anesthesiology, SUNY Downstate Health Science University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
Karen A WongDepartments of Anesthesiology, SUNY Downstate Health Science University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
Lewis M BrownQuantitative Proteomics and Metabolomics Center, Department of Biological Sciences, Columbia University, New York, NY 10027, USA.ORCID 0000-0002-1864-3077
Xiang LiDepartments of Anesthesiology, SUNY Downstate Health Science University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.ORCID 0000-0001-9310-1027
Alus M XiaoliDepartment of Medicine/Endocrinology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0009-0006-4415-9568
Fajun YangDepartment of Medicine/Endocrinology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Ming ZhangDepartments of Anesthesiology, SUNY Downstate Health Science University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
SUNY Downstate Health Sciences University · USAlbert Einstein College of Medicine · USColumbia University · US

Funding

Translational Research CoreP30DK020541 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STREAMSON C CHUA · 2015 to 2026
$27.7M
The Mediator complex in the coordinate regulation of lipogenic gene expressionR01DK110063 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI ELISCOVICH, CAROLINA INES, PESSIN, JEFFREY E. · 2016 to 2025
$5.9M
Novel effectors of insulin action in the liverR01DK117417 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI YANG, FAJUN JAMES · 2020 to 2023
$2.1M
NIDDK NIH HHS P30 DK020541NIDDK NIH HHS R01 DK110063NIDDK NIH HHS R01 DK117417
6 · The paper itself

Abstract

Myocardial ischemia/reperfusion (I/R) elicits an acute inflammatory response involving complement factors. Recently, we reported that myocardial necrosis was decreased in complement C3

Indexed as

Myocardial IschemiaMyocardial Reperfusion InjuryAnimalsApoptosisComplement C3HumansIschemiaMiceMyocardiumMyocytes, CardiacComplement C3apoptosiscomplement C3cytochrome cischemia/reperfusion injury (IRI)pro-caspase 3

Identifiers

PMID37759504
PMCPMC10528058
OpenAlexW4386781689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.