Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 3 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
12 authors at 5 institutions in 1 country.
Kelly C CunninghamDepartment of Internal Medicine-Pulmonary Division, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Deandra R SmithDepartment of Pharmacy Practice and Science, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Daniel N VillageliúDepartment of Internal Medicine-Pulmonary Division, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Christi M EllisDepartment of Internal Medicine-Pulmonary Division, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Amanda E Ramer-TaitDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.ORCID 0000-0003-0950-7548
Jeffrey D PriceDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.
Todd A WyattDepartment of Internal Medicine-Pulmonary Division, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Daren L KnoellDepartment of Internal Medicine-Pulmonary Division, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0002-9977-2857
Mystera M SamuelsonDepartment of Environmental, Agricultural and Occupational Health, College of Public Health, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0002-0754-150X
Patricia E MolinaDepartment of Physiology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.ORCID 0000-0002-3598-384X
David A WelshDepartment of Internal Medicine, Section of Pulmonary/Critical Care & Allergy/Immunology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Derrick R SamuelsonDepartment of Internal Medicine-Pulmonary Division, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0002-5356-1413
University of Nebraska Medical Center · USUniversity of Nebraska–Lincoln · USLouisiana State University Health Sciences Center New Orleans · USNebraska Medical Center · USVA Nebraska Western Iowa Health Care System · US
Funding
UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI PAUL L SORGEN · 2012 to 2026
$59.2M
UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Joann B. Sweasy · 1985 to 2026
$55.0M
Translational Imaging and Behavioral Assessment (TIBA) CoreP20GM130447 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Anna Dunaevsky · 2020 to 2026
$20.7M
The Role of TP-R on Alcohol-Induced Multi-Organ Damage: Liver and HeartP50AA030407 · NIAAA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Carol A. Casey · 2023 to 2026
$7.9M
PILOT--IMPACT OF ALCOHOLISM ON AIDS ASOCIATED MUSCLE WASTINGP50AA009803 · NIAAA · LOUISIANA STATE UNIV HSC NEW ORLEANS · PI NELSON, STEVE · 1994 to 2003
$7.2M
Gut bacterial metallophores in the development and severity of inflammatory bowel diseaseR01DK131990 · NIDDK · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Derrick R Samuelson · 2022 to 2026
$3.3M
Defective Zn Homeostasis impairs host defense against pneumococcal pneumoniaR01HL156952 · NHLBI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI KNOELL, DAREN LEE · 2022 to 2025
$1.5M
Mechanisms by Which Alcohol-Induced Dysbiosis Impairs Host Defense Against Klebsiella PneumoniaeR00AA026336 · NIAAA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI SAMUELSON, DERRICK R · 2019 to 2021
$743k
The role of alcohol-associated microbiota membrane vesicles in mucosal immunityF32AA031180 · NIAAA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI VILLAGELIU, DANIEL · 2023 to 2025
$231k
BLR&D Research Career Scientist ApplicationIK6BX005962 · VA · OMAHA VA MEDICAL CENTER · PI WYATT, TODD A · 2022 to 2025
–
Reactive aldehydes and alcohol misuse in lung infectionsI01BX005886 · VA · OMAHA VA MEDICAL CENTER · PI WYATT, TODD A · 2023 to 2025
Preclinical studies have shown that chronic alcohol abuse leads to alterations in the gastrointestinal microbiota that are associated with behavior changes, physiological alterations, and immunological effects. However, such studies have been limited in their ability to evaluate the direct effects of alcohol-associated dysbiosis. To address this, we developed a humanized alcohol-microbiota mouse model to systematically evaluate the immunological effects of chronic alcohol abuse mediated by intestinal dysbiosis. Germ-free mice were colonized with human fecal microbiota from individuals with high and low Alcohol Use Disorders Identification Test (AUDIT) scores and bred to produce human alcohol-associated microbiota or human control-microbiota F1 progenies. F1 offspring colonized with fecal microbiota from individuals with high AUDIT scores had increased susceptibility to
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Human Alcohol-Microbiota Mice have Increased Susceptibility to Bacterial Pneumonia. · full record | OpenQuestion