Evidence map›Paper›PMID 37759073›Full record

ArticleInfection2024

Cytokine storm and severe hepatitis in pregnancy due to herpes simplex virus 2.

Alessandra Mularoni, Andrea Cona, Lùcia Ribeiro Dias, Matteo Bulati, Rosalia Busà, Salvatore Castelbuono, Davide Lo Porto, Giada Pietrosi, Rosa Liotta, Pier Giulio Conaldi and 2 more

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Alessandra MularoniUnit of Infectious Diseases, ISMETT-IRCCS Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Via Tricomi 5, 90127, Palermo, Italy.
Andrea ConaUnit of Infectious Diseases, ISMETT-IRCCS Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Via Tricomi 5, 90127, Palermo, Italy. acona@ismett.edu.ORCID http://orcid.org/0000-0002-2084-6535
Lùcia Ribeiro DiasUnit of Infectious Diseases, ISMETT-IRCCS Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Via Tricomi 5, 90127, Palermo, Italy.
Matteo BulatiDepartment of Research, ISMETT-IRCCS Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Palermo, Italy.
Rosalia BusàDepartment of Research, ISMETT-IRCCS Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Palermo, Italy.
Salvatore CastelbuonoDepartment of Research, ISMETT-IRCCS Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Palermo, Italy.
Davide Lo PortoUnit of Infectious Diseases, ISMETT-IRCCS Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Via Tricomi 5, 90127, Palermo, Italy.
Giada PietrosiDepartment for the Treatment and Study of Abdominal Disease and Abdominal Transplantation, ISMETT-IRCCS Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Palermo, Italy.
Rosa LiottaPathology Unit, Department of Diagnostic and Therapeutic Services, ISMETT-IRCCS Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Palermo, Italy.
Pier Giulio ConaldiDepartment of Research, ISMETT-IRCCS Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Palermo, Italy.
Paolo Antonio GrossiInfectious and Tropical Diseases Unit, Department of Medicine and Surgery, University of Insubria-ASST-Sette Laghi, Varese, Italy.
Mario LuppiSection of Hematology, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, AOU Modena, 41124, Modena, Italy.
Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione · ITHospital de São João · PTUniversity of Insubria · ITUniversity of Modena and Reggio Emilia · IT

Funding

MUR PNRR Extended Partnership initiative on Emerging Infectious Diseases PE00000007- INF-ACT
6 · The paper itself

Abstract

case presentationA pregnant woman developed hepatitis due to a herpes simplex virus 2 primary infection with a severe systemic inflammatory response. Treatment with acyclovir and human immunoglobulin was given and both mother and baby survived. PURPOSE: We provide the first description of the inflammatory response associated with herpetic hepatitis in pregnancy.

Indexed as

HepatitisHepatitis AHerpes SimplexPregnancy Complications, InfectiousAcyclovirCytokine Release SyndromeFemaleHerpesvirus 2, HumanHumansPregnancyAcyclovirCytokine stormHepatitisHerpes simplex 2PregnancySystemic inflammatory responseViral sepsis

Identifiers

PMID37759073
PMCPMC10811078
OpenAlexW4387113881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.