Evidence map›Paper›PMID 37758867›Full record

ReviewCalcified tissue international2024

Impact of EASO/ESPEN-Defined Sarcopenic Obesity Following a Technology-Based Weight Loss Intervention.

Brian S Wood, Dakota J Batchek, David H Lynch, Hillary B Spangler, Danae C Gross, Curtis L Petersen, John A Batsis

Abstract readReview
In one paragraph

Review in Calcified tissue international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Sarcopenic obesity and weight loss-induced muscle mass loss.Current opinion in clinical nutrition and metabolic care · 2025
    Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Brian S WoodDivision of Geriatric Medicine, UNC School of Medicine, Chapel Hill, NC, USA.ORCID 0000-0001-8914-6476
Dakota J BatchekDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, 5017 Old Clinic Building, Chapel Hill, NC, 27599, USA.
David H LynchDivision of Geriatric Medicine, UNC School of Medicine, Chapel Hill, NC, USA.ORCID 0000-0002-2512-9367
Hillary B SpanglerDivision of Geriatric Medicine, UNC School of Medicine, Chapel Hill, NC, USA.ORCID 0000-0003-4027-4113
Danae C GrossDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, 5017 Old Clinic Building, Chapel Hill, NC, 27599, USA.ORCID 0000-0003-3892-9408
Curtis L PetersenDivision of Geriatric Medicine, UNC School of Medicine, Chapel Hill, NC, USA.ORCID 0000-0002-7210-447X
John A BatsisDivision of Geriatric Medicine, UNC School of Medicine, Chapel Hill, NC, USA. john.batsis@gmail.com.ORCID 0000-0002-0845-4416

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
North Carolina Translational and Clinical Sciences Institute (NC TraCS)UM1TR004406 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NICHOLAS J SHAHEEN · 2023 to 2026
$37.5M
SYNERGY: The Dartmouth Center for clinical and Translational ScienceUL1TR001086 · NCATS · DARTMOUTH COLLEGE · PI GREEN, ALAN I · 2013 to 2017
$18.3M
Health Promotion and Disease Prevention Research CenterU48DP005018 · DP · DARTMOUTH COLLEGE · PI ADACHI-MEJIA, ANNA MARIA · 2014 to 2018
$5.6M
Mobile Health Obesity Wellness Intervention in Rural Older Adults_Res1K23AG051681 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BATSIS, JOHN A. · 2016 to 2022
$1.1M
ACL HHS U48DP005018NCATS NIH HHS UL1 TR001086NCATS NIH HHS UL1 TR002489NCATS NIH HHS UM1 TR004406NCCDPHP CDC HHS U48 DP005018NIA NIH HHS K23 AG051681NIA NIH HHS K23AG051681
6 · The paper itself

Abstract

backgroundSarcopenic Obesity is the co-existence of increased adipose tissue (obesity) and decreased muscle mass or strength (sarcopenia) and is associated with worse outcomes than obesity alone. The new EASO/ESPEN consensus provides a framework to standardize its definition. This study sought to evaluate whether there are preliminary differences observed in weight loss or physical function in older adults with and without sarcopenic obesity taking part in a multicomponent weight loss intervention using these new definitions.

methodsA 6-month, non-randomized, non-blinded, single-arm pilot study was conducted from 2018 to 2020 in adults ≥ 65 years with a body mass index (BMI) ≥ 30 kg/m

resultsIn the parent study, mean weight loss was - 4.6 kg (95% CI - 3.6, - 5.6; p < 0.001). Physical function measures of 30-s sit-to-stand showed a mean increase of 3.1 in sit-to-stand repetitions (+ 1.9, + 4.3; p < 0.001). In this current analysis, there was a significant decrease in weight and an increase in repetitions between baseline and follow-up within each group of individuals with and without sarcopenia for each of the proposed definitions. However, we did not observe any significant differences in the changes between groups from baseline to follow-up.

conclusionsThe potential lack of significant differences in weight loss or physical function between older adults with and without sarcopenic obesity participating in a weight loss intervention may suggest that well-designed, multicomponent interventions can lead to similar outcomes irrespective of sarcopenia status in persons with obesity. Fully powered randomized clinical trials are critically needed to confirm these preliminary results.

Indexed as

SarcopeniaAgedHumansMuscle StrengthObesityPilot ProjectsRetrospective StudiesWeight LossClinical trialsObesitySarcopeniaWeight loss

Identifiers

PMID37758867
PMCPMC11193940

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.