Evidence map›Paper›PMID 37758829›Full record

ReviewNPJ digital medicine2023

Systematic review of deep learning image analyses for the diagnosis and monitoring of skin disease.

Shern Ping Choy, Byung Jin Kim, Alexandra Paolino, Wei Ren Tan, Sarah Man Lin Lim, Jessica Seo, Sze Ping Tan, Luc Francis, Teresa Tsakok, Michael Simpson and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in NPJ digital medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
17.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 76 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Current research landscape and future prospects of in silico modeling approaches for atopic dermatitis.JID innovations : skin science from molecules to population health · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Improving Clinical Reliability of Diffusion-Based Dermatology Image Synthesis Through Synthetic Note Alignment and Post-Generation Filtering.IEEE International Conference on Omni-layer Intelligent Systems : COINS. IEEE International Conference on Omni-layer Intelligent Systems · 2026
    Article
  12. Review
  13. Review
  14. Article
  15. [The analysis of invention patents in the field of artificial intelligent medical devices].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Shern Ping Choy *St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK.ORCID http://orcid.org/0000-0001-5891-6511
Byung Jin Kim *St George's University Hospitals NHS Foundation Trust, London, UK.
Alexandra Paolino *St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK.
Wei Ren Tan *St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK.
Sarah Man Lin LimMaidstone and Tunbridge Wells NHS Trust, Kent, UK.
Jessica SeoImperial College London, London, UK.
Sze Ping TanBarking, Havering and Redbridge University Hospitals NHS Trust, London, UK.
Luc FrancisSt John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK.
Teresa TsakokSt John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK.
Michael SimpsonDepartment of Medical and Molecular Genetics, King's College London, London, UK.
Jonathan N W N BarkerSt John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK.
Magnus D LynchSt John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK.
Mark S CorbettCenter for Reviews and Dissemination, University of York, York, UK.
Catherine H SmithSt John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK.
Satveer K MahilSt John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK. satveer.mahil@kcl.ac.uk.ORCID http://orcid.org/0000-0003-4692-3794
King's College London · GBBarking, Havering And Redbridge University Hospitals NHS Trust · GBImperial College London · GBMaidstone and Tunbridge Wells NHS Trust · GBSt George’s University Hospitals NHS Foundation Trust · GBUniversity of York · GB

Funding

DH | National Institute for Health Research (NIHR) NIHR302258Medical Research Council MR/R001839/1Psoriasis Association PhD StudentshipRCUK | Medical Research Council (MRC) [MR/R001839/1]
6 · The paper itself

Abstract

Skin diseases affect one-third of the global population, posing a major healthcare burden. Deep learning may optimise healthcare workflows through processing skin images via neural networks to make predictions. A focus of deep learning research is skin lesion triage to detect cancer, but this may not translate to the wider scope of >2000 other skin diseases. We searched for studies applying deep learning to skin images, excluding benign/malignant lesions (1/1/2000-23/6/2022, PROSPERO CRD42022309935). The primary outcome was accuracy of deep learning algorithms in disease diagnosis or severity assessment. We modified QUADAS-2 for quality assessment. Of 13,857 references identified, 64 were included. The most studied diseases were acne, psoriasis, eczema, rosacea, vitiligo, urticaria. Deep learning algorithms had high specificity and variable sensitivity in diagnosing these conditions. Accuracy of algorithms in diagnosing acne (median 94%, IQR 86-98; n = 11), rosacea (94%, 90-97; n = 4), eczema (93%, 90-99; n = 9) and psoriasis (89%, 78-92; n = 8) was high. Accuracy for grading severity was highest for psoriasis (range 93-100%, n = 2), eczema (88%, n = 1), and acne (67-86%, n = 4). However, 59 (92%) studies had high risk-of-bias judgements and 62 (97%) had high-level applicability concerns. Only 12 (19%) reported participant ethnicity/skin type. Twenty-four (37.5%) evaluated the algorithm in an independent dataset, clinical setting or prospectively. These data indicate potential of deep learning image analysis in diagnosing and monitoring common skin diseases. Current research has important methodological/reporting limitations. Real-world, prospectively-acquired image datasets with external validation/testing will advance deep learning beyond the current experimental phase towards clinically-useful tools to mitigate rising health and cost impacts of skin disease.

Identifiers

PMID37758829
PMCPMC10533565
OpenAlexW4387104519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.