Evidence map›Paper›PMID 37758767›Full record

ArticleScientific reports2023

Validating virtual administration of neuropsychological testing in Parkinson disease: a pilot study.

Julia Gallagher, Eugenia Mamikonyan, Sharon X Xie, Baochan Tran, Sarah Shaw, Daniel Weintraub

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Julia GallagherDepartment of Neurology, Perelman School of Medicine at the University of Pennsylvania, 3615 Chestnut St., Philadelphia, PA, 19104, USA.
Eugenia MamikonyanDepartment of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Sharon X XieDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Baochan TranDepartment of Neurology, Perelman School of Medicine at the University of Pennsylvania, 3615 Chestnut St., Philadelphia, PA, 19104, USA.
Sarah ShawDepartment of Neurology, Perelman School of Medicine at the University of Pennsylvania, 3615 Chestnut St., Philadelphia, PA, 19104, USA.
Daniel WeintraubDepartment of Neurology, Perelman School of Medicine at the University of Pennsylvania, 3615 Chestnut St., Philadelphia, PA, 19104, USA. daniel.weintraub@pennmedicine.upenn.edu.
University of Pennsylvania · USVeterans Health Administration · US

Funding

Research Education ComponentP30AG072979 · NIA · UNIVERSITY OF PENNSYLVANIA · PI DAVID A WOLK · 2021 to 2026
$24.8M
Project IV "Tackling Heterogeneity of Cognitive Trajectory in LBD"U19AG062418 · NIA · UNIVERSITY OF PENNSYLVANIA · PI LEE, VIRGINIA M · 2019 to 2023
$18.1M
NIA NIH HHS P30 AG072979NIA NIH HHS U19 AG062418
6 · The paper itself

Abstract

COVID-19 has highlighted the need for remote cognitive testing, but the reliability and validity of virtual cognitive testing in Parkinson disease (PD) is unknown. Therefore, we assessed PD participants enrolled in an observational, cognition-focused study with an extensive cognitive battery completed both in-person and via video conference close in time. Data for 35 PD participants with normal cognition to mild dementia were analyzed. Only one test (semantic verbal fluency) demonstrated a difference in score by administration type, with a significantly better score virtually. Only three tests demonstrated good reliability for in-person versus virtual testing, but reliability values for visit 1 versus visit 2 were similarly low overall. Trail Making Test B was successfully administered virtually to only 18 participants due to technical issues. Virtual and in-person cognitive testing generate similar scores at the group level, but with poor to moderate reliability for most tests. Mode of test administration, learning effects, and technical difficulties explained little of the low test-retest reliability, indicating possible significant short-term variability in cognitive performance in PD in general, which has implications for clinical care and research. In-person cognitive testing with a neuropsychologist remains the gold standard, and it remains to be determined if virtual cognitive testing is feasible in PD.

Indexed as

Cognition DisordersCognitive DysfunctionParkinson DiseaseHumansNeuropsychological TestsPilot ProjectsReproducibility of Results

Identifiers

PMID37758767
PMCPMC10533878
OpenAlexW4387097619

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.