Evidence map›Paper›PMID 37758700›Full record

ArticleNature communications2023

Lung extracellular matrix modulates KRT5

Richard J Hewitt, Franz Puttur, David C A Gaboriau, Frédéric Fercoq, Maryline Fresquet, William J Traves, Laura L Yates, Simone A Walker, Philip L Molyneaux, Samuel V Kemp and 8 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
13.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Beyond the epithelium: multicellular niches in lung regeneration and disease.American journal of physiology. Lung cellular and molecular physiology · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Sex Differences in Lung Immunity.Immunological reviews · 2026
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 2 countries.

Richard J HewittNational Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.ORCID http://orcid.org/0000-0003-4294-0052
Franz PutturNational Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.
David C A GaboriauFacility for Imaging by Light Microscopy, National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.ORCID http://orcid.org/0000-0003-4047-6487
Frédéric FercoqCancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.ORCID http://orcid.org/0000-0002-4825-024X
Maryline FresquetWellcome Centre for Cell-Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK.
William J TravesNational Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.
Laura L YatesNational Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.
Simone A WalkerNational Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.
Philip L MolyneauxNational Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.ORCID http://orcid.org/0000-0003-1301-8800
Samuel V KempRoyal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, SW3 6NP, UK.ORCID http://orcid.org/0000-0002-6639-0166
Andrew G NicholsonRoyal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, SW3 6NP, UK.
Alexandra RiceRoyal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, SW3 6NP, UK.
Edward RobertsCancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.ORCID http://orcid.org/0000-0002-8229-1715
Rachel LennonWellcome Centre for Cell-Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK.ORCID http://orcid.org/0000-0001-6400-0227
Leo M CarlinCancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.ORCID http://orcid.org/0000-0001-7172-5234
Adam J ByrneNational Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.
Toby M MaherNational Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.
Clare M LloydNational Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK. c.lloyd@imperial.ac.uk.ORCID http://orcid.org/0000-0001-8977-6726
Imperial College London · GBGuy's and St Thomas' NHS Foundation Trust · GBCancer Research UK Scotland Institute · GBWellcome Centre for Cell-Matrix Research · GBKeck Hospital of USC · USLung Institute · USNottingham University Hospitals NHS Trust · GB

Funding

Biotechnology and Biological Sciences Research Council BB/L015129/1Cancer Research UK 23983Cancer Research UK A23983Cancer Research UK A31287Department of Health CS-2013-13-017Department of Health P89068HSRD VA CDA 13-017Wellcome TrustWellcome Trust 104931/Z/14/ZWellcome Trust 107059/Z/15/ZWellcome Trust 202860/Z/16/ZWellcome Trust 203128/Z/16/Z
6 · The paper itself

Abstract

Aberrant expansion of KRT5

Indexed as

Idiopathic Pulmonary FibrosisAlveolar Epithelial CellsBiological TransportCell MovementExtracellular MatrixHumansKeratin-5Keratin-5KRT5 protein, human

Identifiers

PMID37758700
PMCPMC10533905
OpenAlexW4387091760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.