Evidence map›Paper›PMID 37757586›Full record

ReviewCurrent opinion in neurobiology2023

Low- and high-level coordination of orofacial motor actions.

David Kleinfeld, Martin Deschênes, Michael N Economo, Michaël Elbaz, David Golomb, Song-Mao Liao, Daniel H O'Connor, Fan Wang

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Mice navigate scent trails using predictive policies.bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Cerebellar control of targeted tongue movements.The Journal of physiology · 2025
    Article
  10. A brainstem map of orofacial rhythms.bioRxiv : the preprint server for biology · 2025
    Article
  11. Article
  12. Hand-Jaw Coordination as Mice Handle Food Is Organized around Intrinsic Structure-Function Relationships.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  13. Molecular Organization of Autonomic, Respiratory, and Spinally-Projecting Neurons in the Mouse Ventrolateral Medulla.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David KleinfeldDepartment of Physics, University of California at San Diego, La Jolla, CA 92093, USA; Department of Neurobiology, University of California at San Diego, La Jolla, CA 92093, USA. Electronic address: dk@physics.ucsd.edu.
Martin DeschênesDepartment of Psychiatry and Neuroscience, Laval University, Québec City, G1J 2R3 Canada.
Michael N EconomoDepartment of Bioengineering, Boston University, Boston, MA 02215, USA.
Michaël ElbazDepartment of Neurobiology, Northwestern University, Evanston, IL 60208, USA.
David GolombDepartment of Physiology and Cell Biology, Ben Gurion University, Be'er-Sheba 8410501, Israel; Department of Physics, Ben Gurion University, Be'er-Sheba 8410501, Israel.
Song-Mao LiaoDepartment of Physics, University of California at San Diego, La Jolla, CA 92093, USA.
Daniel H O'ConnorDepartment of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Zynval Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, MD 21218, USA.
Fan WangDepartment of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; McGovern Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Funding

Top-down and bottom-up signals for flexible orofacial behaviorsU19NS137920 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI David Kleinfeld · 2024 to 2026
$15.9M
Theory and Modeling of the Orofacial Active SensationU19NS107466 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FREUND, YOAV SHAI · 2018 to 2022
$14.9M
Pre-motor Neural Circuits for Exploratory MovementR01NS077986 · NINDS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI WANG, FAN · 2013 to 2022
$3.4M
NINDS NIH HHS R01 NS077986NINDS NIH HHS U19 NS107466NINDS NIH HHS U19 NS137920
6 · The paper itself

Abstract

Orofacial motor actions are movements that, in rodents, involve whisking of the vibrissa, deflection of the nose, licking and lapping with the tongue, and consumption through chewing. These actions, along with bobbing and turning of the head, coordinate to subserve exploration while not conflicting with life-supporting actions such as breathing and swallowing. Orofacial and head movements are comprised of two additive components: a rhythm that can be entrained by the breathing oscillator and a broadband component that directs the actuator to the region of interest. We focus on coordinating the rhythmic component of actions into a behavior. We hypothesize that the precise timing of each constituent action is continually adjusted through the merging of low-level oscillator input with sensory-derived, high-level rhythmic feedback. Supporting evidence is discussed.

Indexed as

MovementNoseAnimalsRespirationRodentiaVibrissae

Identifiers

PMID37757586
PMCPMC11034851

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.