ArticleAmerican journal of respiratory and critical care medicine2023
Activation of CD8
Open access · greenAbstract read
In one paragraph
Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
14.3field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 85 citations in OpenAlex.
- Preclinical models of COPD: a state of the art review.The European respiratory journal · 2026Review
- The IL-33/ST2 pathway to modulate the inflammatory microenvironment: A new therapeutic target in chronic obstructive pulmonary disease.Biochemistry and biophysics reports · 2026Review
- Integrative Omics of Eosinophils in Asthma and COPD: Deciphering Molecular Signatures for Targeted Therapy.Molecular diagnosis & therapy · 2026Review
- AARS1-Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Airway cell-cell communication in smoking through integration of spatial and single-cell transcriptomics.Respiratory research · 2026Article
- Modelling cigarette smoke-induced lung vascular dysfunction using an alveolus-on-chip.Materials today. Bio · 2026Article
- Defective alveolar regeneration in emphysema: identifying dysfunctional cellular crosstalk and novel therapeutic opportunities for tissue repair.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Spatial transcriptomics reveals compartment-specific cytotoxic T cell crosstalk with AT2 and goblet cells in advanced COPD.Biomarker research · 2026Article
- Hallmarks of the ageing lung: 10 years later.The European respiratory journal · 2026Review
- Tissue-resident memory T cells in organ transplantation: implications for immune homeostasis and graft outcomes.Inflammation and regeneration · 2026Review
- HLA-DRA-mediated inhibition of T-Cell proliferation by differentiated airway epithelium and its disruption in smoking-associated airway inflammation.Respiratory research · 2026Article
- PROK2 defines a pathogenic neutrophil subset and serves as a clinical indicator of neutrophilic inflammation in COPD.Respiratory research · 2026Article
- Single-Cell RNA Sequencing of Human Lung Tissues Reveals Metallothionein-Positive T Cells as a Novel Potential Marker of Susceptibility to Chronic Obstructive Pulmonary Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Regulation of basal and tumour necrosis factor α-induced fibroblast gene expression by peptidylarginine deiminase 2.The Journal of physiology · 2026Article
- CD207-Positive Dendritic Cells Promote Emphysema Through CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- New approaches to uncover COPD pathobiology and develop therapies.JCI insight · 2026Review
- Chronic IL-21 exposure reshapes pulmonary environment, elevating risk of respiratory diseases.Cellular and molecular life sciences : CMLS · 2026Article
- Impact of chronic obstructive pulmonary disease on mortality in elderly patients with hip fracture: A retrospective cohort study.PloS one · 2026Article
- The gut-lung axis in COPD: immunomodulatory roles of gut microbiota and novel therapeutic strategies.Frontiers in immunology · 2026Review
- The role of programmed cell death in chronic obstructive pulmonary disease: from pathogenesis to treatment.Frontiers in immunology · 2026Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
22 authors at 5 institutions in 2 countries.
Ana B Villaseñor-AltamiranoDivision of Pulmonary and Critical Care Medicine.ORCID 0000-0002-3940-5617
Dhawal JainPulmonary Drug Discovery Laboratory, Pharmaceuticals Research and Development, Bayer US LLC, Boston, Massachusetts; and.ORCID 0000-0001-9437-7201
Yunju JeongDivision of Pulmonary and Critical Care Medicine.ORCID 0000-0002-0453-3475
Jaivardhan A MenonDivision of Pulmonary and Critical Care Medicine.
Mari KamiyaDivision of Pulmonary and Critical Care Medicine.ORCID 0000-0002-2093-3823
Hibah HaiderDivision of Pulmonary and Critical Care Medicine.ORCID 0000-0001-5041-1068
Reshmi ManandharDivision of Pulmonary and Critical Care Medicine.ORCID 0009-0005-9938-6410
Muhammad Dawood Amir SheikhDivision of Pulmonary and Critical Care Medicine.ORCID 0000-0002-5029-4161
Humra AtharDivision of Pulmonary and Critical Care Medicine.
Louis T MerriamDivision of Pulmonary and Critical Care Medicine.ORCID 0000-0002-3731-6792
Min Hyung RyuChanning Division of Network Medicine, and.ORCID 0000-0003-3071-7363
Takanori SasakiDivision of Rheumatology, Inflammation, and Immunity, Department of Medicine, and.
Peter J CastaldiChanning Division of Network Medicine, and.
Deepak A RaoDivision of Rheumatology, Inflammation, and Immunity, Department of Medicine, and.ORCID 0000-0001-9672-7746
Lynette M ShollDepartment of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.
Marina ViveroDepartment of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0001-7176-679X
Craig P HershChanning Division of Network Medicine, and.ORCID 0000-0002-1342-4334
Xiaobo ZhouChanning Division of Network Medicine, and.ORCID 0000-0002-7127-2869
Justus VeerkampPharmaceuticals, Research & Early Development Precision Medicine RED (preMED), Pharmaceuticals Research and Development, Bayer AG, Wuppertal, Germany.
Jeong H YunChanning Division of Network Medicine, and.ORCID 0000-0002-4361-8295
Edy Y KimDivision of Pulmonary and Critical Care Medicine.ORCID 0000-0002-9095-3109
MassGeneralBrigham - Bayer Pulmonary Drug Discovery Laboratory
Harvard University · USPulmonary and Critical Care Associates · USBayer (United States) · USBrigham and Women's Hospital · USBayer (Germany) · DE
Funding
Using Integrative Genomics To Identify and Characterize Emphysema-Associated eQTLR01HL124233 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CASTALDI, PETER · 2014 to 2024
$7.1MSpecialized Pro-Resolving Mediators in AsthmaR01HL122531 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LEVY, BRUCE D · 2014 to 2024
$4.7MThe role of Bik in the replication and severity of influenza A virusR01AI148180 · NIAID · OHIO STATE UNIVERSITY · PI MEBRATU, YOHANNES AFEWORK · 2021 to 2025
$2.1MProspective Health Outcomes and Inflammatory Biomarkers Associated with e-Cigarette UseR01HL147326 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CASTALDI, PETER · 2019 to 2021
$1.5MThe role of COPD genetic risk factor HHIP on lymphocytic inflammationK08HL146972 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI YUN, JEONG H · 2020 to 2024
$848kAmerican Heart Association-American Stroke Association 867587NHLBI NIH HHS K08 HL146972NHLBI NIH HHS R01 HL122531NHLBI NIH HHS R01 HL124233NHLBI NIH HHS R01 HL147326NIAID NIH HHS R01 AI148180
Abstract
PubMed holds no abstract for this paper.
Indexed as
CD8-Positive T-LymphocytesPulmonary Disease, Chronic ObstructiveAnimalsDisease Models, AnimalHumansInflammationLungMiceProteomicsReceptors, Antigen, T-CellReceptors, Antigen, T-Cellchronic obstructive pulmonary diseasememory T cellsmultiomicsproteomicsRNA sequence analysis
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.