Evidence map›Paper›PMID 37756405›Full record

ArticleScience advances2023

A wireless, solar-powered, optoelectronic system for spatial restriction-free long-term optogenetic neuromodulations.

Jaejin Park, Kyubeen Kim, Yujin Kim, Tae Soo Kim, In Sik Min, Bowen Li, Young Uk Cho, Chanwoo Lee, Ju Young Lee, Yuyan Gao and 9 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

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  8. Review
  9. Genetics-Based Targeting Strategies for Precise Neuromodulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  10. Review
  11. Multifunctional bioelectronics for brain-body circuits.Nature reviews bioengineering · 2025
    Article
  12. Article
  13. Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 3 countries.

Jaejin ParkFunctional Bio-integrated Electronics and Energy Management Lab, School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.ORCID 0009-0000-1919-3306
Kyubeen KimFunctional Bio-integrated Electronics and Energy Management Lab, School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.ORCID 0000-0002-7425-2871
Yujin KimDepartment of Biomedical Sciences, College of Medicine, Korea University, 73 Goryeodae-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.
Tae Soo KimFunctional Bio-integrated Electronics and Energy Management Lab, School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.ORCID 0000-0001-9052-9140
In Sik MinFunctional Bio-integrated Electronics and Energy Management Lab, School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.ORCID 0009-0003-0314-4915
Bowen LiDepartment of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0003-4893-0525
Young Uk ChoFunctional Bio-integrated Electronics and Energy Management Lab, School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.ORCID 0000-0003-2578-5177
Chanwoo LeeFunctional Bio-integrated Electronics and Energy Management Lab, School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.
Ju Young LeeFunctional Bio-integrated Electronics and Energy Management Lab, School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.ORCID 0000-0003-3349-0248
Yuyan GaoDepartment of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-8955-627X
Kyowon KangFunctional Bio-integrated Electronics and Energy Management Lab, School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.
Do Hyeon KimSchool of Electrical Engineering and Computer Science (EECS), Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Republic of Korea.ORCID 0000-0003-3060-1192
Won Jun ChoiCenter for Opto-Electronic Materials and Devices, Korea Institute of Science and Technology (KIST), Seoul 02792, Korea.
Hyun-Beom ShinKorea Advanced Nano Fab Center (KANC), Suwon 443-270, Korea.ORCID 0000-0001-9019-5937
Ho Kwan KangKorea Advanced Nano Fab Center (KANC), Suwon 443-270, Korea.
Young Min SongSchool of Electrical Engineering and Computer Science (EECS), Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Republic of Korea.ORCID 0000-0002-4473-6883
Huanyu ChengDepartment of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0001-6075-4208
Il-Joo ChoDepartment of Biomedical Sciences, College of Medicine, Korea University, 73 Goryeodae-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.ORCID 0000-0001-9016-6749
Ki Jun YuFunctional Bio-integrated Electronics and Energy Management Lab, School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.ORCID 0000-0002-2922-2702
Yonsei University · KRPennsylvania State University · USGwangju Institute of Science and Technology · KRKorea Advanced Nano Fab Center · KRKorea University · JPKorea Institute of Science and Technology · KR

Funding

Smart skin grafts for quantitative assessment and treatment of diabetic woundsR21EB030140 · NIBIB · PENNSYLVANIA STATE UNIVERSITY, THE · PI CHENG, HUANYU · 2021 to 2021
$620k
NIBIB NIH HHS R21 EB030140
6 · The paper itself

Abstract

Numerous wireless optogenetic systems have been reported for practical tether-free optogenetics in freely moving animals. However, most devices rely on battery-powered or coil-powered systems requiring periodic battery replacement or bulky, high-cost charging equipment with delicate antenna design. This leads to spatiotemporal constraints, such as limited experimental duration due to battery life or animals' restricted movement within specific areas to maintain wireless power transmission. In this study, we present a wireless, solar-powered, flexible optoelectronic device for neuromodulation of the complete freely behaving subject. This device provides chronic operation without battery replacement or other external settings including impedance matching technique and radio frequency generators. Our device uses high-efficiency, thin InGaP/GaAs tandem flexible photovoltaics to harvest energy from various light sources, which powers Bluetooth system to facilitate long-term, on-demand use. Observation of sustained locomotion behaviors for a month in mice via secondary motor cortex area stimulation demonstrates the notable capabilities of our device, highlighting its potential for space-free neuromodulating applications.

Indexed as

OptogeneticsWireless TechnologyAnimalsElectric Power SuppliesMiceMovement

Identifiers

PMID37756405
PMCPMC10530225
OpenAlexW4387092118

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.