Evidence map›Paper›PMID 37756354›Full record

ArticlePloS one2023

The relationship between visual function and physical performance in the Study of Muscle, Mobility and Aging (SOMMA).

Atalie C Thompson, Eileen Johnson, Michael E Miller, Jeff D Williamson, Anne B Newman, Steve Cummings, Peggy Cawthon, Stephen B Kritchevsky

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  6. Relationship of Multiple Sensory Impairments With Physical Performance in Older Adults in the Study of Muscle, Mobility and Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Atalie C ThompsonDepartment of Ophthalmology, Wake Forest University School of Medicine, Winston Salem, NC, United States of America.ORCID 0000-0002-2817-6417
Eileen JohnsonSan Francisco Coordinating Center, California Pacific Medical Center Research Institute, San Francisco, California, United States of America.
Michael E MillerDivision of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC, United States of America.
Jeff D WilliamsonDepartment of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston Salem, NC, United States of America.
Anne B NewmanCenter for Aging and Population Health, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.
Steve CummingsSan Francisco Coordinating Center, California Pacific Medical Center Research Institute, San Francisco, California, United States of America.
Peggy CawthonSan Francisco Coordinating Center, California Pacific Medical Center Research Institute, San Francisco, California, United States of America.
Stephen B KritchevskyDepartment of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston Salem, NC, United States of America.
Wake Forest University · USUniversity of California, San Francisco · USCalifornia Pacific Medical Center · USUniversity of Pittsburgh · US

Funding

Study of Muscle, Mobility and Aging: SOMMA2R01AG059416 · NIA · CALIFORNIA PACIFIC MED CTR RES INSTITUTE · PI STEVEN RON CUMMINGS, Peggy Mannen Cawthon · 2018 to 2026
$70.3M
Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI LEON LENCHIK · 2002 to 2026
$36.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
Deep learning to quantify glaucomatous damage on fundus photographs for teleophthalmologyK23EY030897 · NEI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI THOMPSON, ATALIE C · 2020 to 2024
$968k
NCATS NIH HHS UL1 TR001420NEI NIH HHS K23 EY030897NIA NIH HHS P30 AG021332NIA NIH HHS P30 AG024827NIA NIH HHS R01 AG059416
6 · The paper itself

Abstract

purposeThe relationship of types of visual function to different aspects of physical function, especially strength and coordination, has been understudied, but delineation of these relationships could suggest potentially modifiable targets prior to the onset of disability.

methodsCross-sectional analysis of visual function (self-reported eyesight and eye disease, visual acuity, contrast sensitivity) and physical function tests in 877 older adults (mean age 76.36±5.01 years, 59.2% women, and 13.3% Black race). Separate linear regression models were constructed for short physical performance battery (SPPB), expanded SPPB (eSPPB), their components (gait speed, chair stand, balance, narrow walk), stair climb, four-square step, leg extension peak power and strength, and grip strength.

resultsIn adjusted models, worse acuity, worse contrast sensitivity, and self-reported poor vision were significantly associated with worse performance on the eSPPB and four-square step test. Worse contrast sensitivity, but not acuity, was significantly associated with shorter balance times, slower chair stand pace, longer stair climb time, and worse SPPB score. Associations of worse acuity and contrast sensitivity with weaker leg extension power, leg strength, and grip strength were attenuated by covariate adjustment. Self-reported macular degeneration, but not cataract or glaucoma, was associated with worse performance on SPPB, eSPPB, balance, stair climb, and four-square step tests in adjusted models. Worse contrast sensitivity and macular degeneration remained associated with worse SPPB and balance after controlling for visual acuity and self-reported eyesight.

conclusionsPoor contrast sensitivity was more strongly associated with worse physical performance than acuity, especially for complex tasks that dynamically challenge coordination and balance. Future studies should examine if older adults with contrast sensitivity impairment would benefit from targeted intervention to decrease their risk of disability.

Indexed as

Macular DegenerationMusclesAgedAged, 80 and overAgingCross-Sectional StudiesFemaleHumansMaleVisual Acuity

Identifiers

PMID37756354
PMCPMC10529600
OpenAlexW4387092722

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.