Evidence map›Paper›PMID 37755956›Full record

ArticleToxins2023

Intramuscular Bleeding and Formation of Microthrombi during Skeletal Muscle Damage Caused by a Snake Venom Metalloprotease and a Cardiotoxin.

Medha Sonavane, José R Almeida, Elanchezhian Rajan, Harry F Williams, Felix Townsend, Elizabeth Cornish, Robert D Mitchell, Ketan Patel, Sakthivel Vaiyapuri

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Medha SonavaneSchool of Pharmacy, University of Reading, Reading RG6 6UB, UK.
José R AlmeidaSchool of Pharmacy, University of Reading, Reading RG6 6UB, UK.ORCID 0000-0002-4637-4468
Elanchezhian RajanSchool of Pharmacy, University of Reading, Reading RG6 6UB, UK.ORCID 0000-0002-6257-3678
Harry F WilliamsToxiven Biotech Private Limited, Coimbatore 641042, Tamil Nadu, India.ORCID 0000-0001-5095-3131
Felix TownsendSchool of Biological Sciences, University of Reading, Reading RG6 6UB, UK.
Elizabeth CornishSchool of Biological Sciences, University of Reading, Reading RG6 6UB, UK.
Robert D MitchellMicregen Ltd., Thames Valley Science Park, Reading RG2 9LH, UK.
Ketan PatelSchool of Biological Sciences, University of Reading, Reading RG6 6UB, UK.
Sakthivel VaiyapuriSchool of Pharmacy, University of Reading, Reading RG6 6UB, UK.ORCID 0000-0002-6006-6517
University of Reading · GB

Funding

British Heart Foundation PG/19/62/34593Medical Research Council reference: MR/W019353/1
6 · The paper itself

Abstract

The interactions between specific snake venom toxins and muscle constituents are the major cause of severe muscle damage that often result in amputations and subsequent socioeconomic ramifications for snakebite victims and/or their families. Therefore, improving our understanding of venom-induced muscle damage and determining the underlying mechanisms of muscle degeneration/regeneration following snakebites is critical to developing better strategies to tackle this issue. Here, we analysed intramuscular bleeding and thrombosis in muscle injuries induced by two different snake venom toxins (CAMP-

Indexed as

CrotalusSnake BitesThrombosisVenomous SnakesCardiotoxinsElapid VenomsFibrinogenHemorrhageHumansIntegrinsMetalloproteasesMuscle, SkeletalSnake VenomsCardiotoxinsElapid VenomsFibrinogenIntegrinsMetalloproteasesSnake Venomsbleedingcardiotoxinmetalloproteasemicrothrombimuscle damagethrombosis

Identifiers

PMID37755956
PMCPMC10536739
OpenAlexW4386254992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.