Evidence map›Paper›PMID 37755947›Full record

ArticleToxins2023

Evaluation of Statistical Treatment of Left-Censored Contamination Data: Example Involving Deoxynivalenol Occurrence in Pasta and Pasta Substitute Products.

Alessandro Feraldi, Barbara De Santis, Marco Finocchietti, Francesca Debegnach, Antonio Mandile, Marco Alfò

Abstract read
In one paragraph

Article in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alessandro FeraldiDepartment of Statistical Science, University of Rome "La Sapienza", 00185 Rome, Italy.
Barbara De SantisDepartment of Food Safety, Nutrition and Veterinary Public Health, Italian National Institute of Health, 00161 Rome, Italy.ORCID 0000-0003-4210-2796
Marco FinocchiettiDepartment of Statistical Science, University of Rome "La Sapienza", 00185 Rome, Italy.
Francesca DebegnachDepartment of Food Safety, Nutrition and Veterinary Public Health, Italian National Institute of Health, 00161 Rome, Italy.ORCID 0000-0002-8447-5948
Antonio MandileDepartment of Statistical Science, University of Rome "La Sapienza", 00185 Rome, Italy.
Marco AlfòDepartment of Statistical Science, University of Rome "La Sapienza", 00185 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The handling of data on food contamination frequently represents a challenge because these are often left-censored, being composed of both positive and non-detected values. The latter observations are not quantified and provide only the information that they are below a laboratory-specific threshold value. Besides deterministic approaches, which simplify the treatment through the substitution of non-detected values with fixed threshold or null values, a growing interest has been shown in the application of stochastic approaches to the treatment of unquantified values. In this study, a multiple imputation procedure was applied in order to analyze contamination data on deoxynivalenol, a mycotoxin that may be present in pasta and pasta substitute products. An application of the proposed technique to censored deoxynivalenol occurrence data is presented. The results were compared to those attained using deterministic techniques (substitution methods). In this context, the stochastic approach seemed to provide a more accurate, unbiased and realistic solution to the problem of left-censored occurrence data. The complete sample of values could then be used to estimate the exposure of the general population to deoxynivalenol based on consumption data.

Indexed as

MycotoxinsTrichothecenesFood ContaminationHumansdeoxynivalenolMycotoxinsTrichotheceneschemical contaminantsdietary exposureleft-censored datalimit of quantification

Identifiers

PMID37755947
PMCPMC10536512

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.