Evidence map›Paper›PMID 37755490›Full record

ArticleAnalytical and bioanalytical chemistry2023

Distinctive calcium isotopic composition of mice organs and fluids: implications for biological research.

Meng-Meng Cui, Frédéric Moynier, Ben-Xun Su, Wei Dai, Brandon Mahan, Marie Le Borgne

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Meng-Meng CuiKey Laboratory of Mineral Resources, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing, 100029, China. cuimm@mail.iggcas.ac.cn.
Frédéric MoynierInstitut de Physique du Globe de Paris, Université Paris Cité, CNRS, 1 Rue Jussieu, 75005, Paris, France. moynier@ipgp.fr.
Ben-Xun SuKey Laboratory of Mineral Resources, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing, 100029, China.
Wei DaiInstitut de Physique du Globe de Paris, Université Paris Cité, CNRS, 1 Rue Jussieu, 75005, Paris, France.
Brandon MahanEarth and Environmental Sciences, James Cook University, Townsville, Australia.
Marie Le BorgneUniversité Paris Cité and Université Sorbonne Paris Nord, INSERM, 75018, Paris, LVTS, France.

Funding

European Research Council (ERC) for the Proof of Concept Grant 101059236
6 · The paper itself

Abstract

The stable calcium (Ca) isotopes offer a minimally invasive method for assessing Ca balance in the body, providing a new avenue for research and clinical applications. In this study, we measured the Ca isotopic composition of soft tissues (brain, muscle, liver, and kidney), mineralized tissue (bone), and blood (plasma) from 10 mice (5 females and 5 males) with three different genetic backgrounds and same age (3 months old). The results reveal a distinctive Ca isotopic composition in different body compartments of mice, primally controlled by each compartment's unique Ca metabolism and genetic background, independent of sex. The bones are enriched in the lighter Ca isotopes (δ

Indexed as

Body FluidsCalciumCalcium IsotopesAnimalsBone and BonesBrainFemaleKidneyLiverMaleMiceMice, Inbred C57BLCalciumCalcium IsotopesBody compartmentsCalcium isotopesGenetic backgroundIsotope fractionationSex

Identifiers

PMID37755490

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.