Evidence map›Paper›PMID 37755398›Full record

ReviewPathophysiology : the official journal of the International Society for Pathophysiology2023

Pathophysiology, Management, and Therapeutics in Subarachnoid Hemorrhage and Delayed Cerebral Ischemia: An Overview.

Henry W Sanicola, Caleb E Stewart, Patrick Luther, Kevin Yabut, Bharat Guthikonda, J Dedrick Jordan, J Steven Alexander

Open access · goldAbstract readReview
In one paragraph

Review in Pathophysiology : the official journal of the International Society for Pathophysiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Henry W SanicolaDepartment of Neurology, Louisiana State University Health Sciences Center in Shreveport, Shreveport, LA 71103, USA.ORCID 0000-0002-8117-8075
Caleb E StewartDepartment of Neurosurgery, Louisiana State University Health Sciences Center in Shreveport, Shreveport, LA 71103, USA.
Patrick LutherSchool of Medicine, Louisiana State University Health Sciences Center in Shreveport, Shreveport, LA 71103, USA.
Kevin YabutSchool of Medicine, Louisiana State University Health Sciences Center in Shreveport, Shreveport, LA 71103, USA.ORCID 0009-0001-9556-492X
Bharat GuthikondaDepartment of Neurosurgery, Louisiana State University Health Sciences Center in Shreveport, Shreveport, LA 71103, USA.
J Dedrick JordanDepartment of Neurology, Louisiana State University Health Sciences Center in Shreveport, Shreveport, LA 71103, USA.ORCID 0000-0002-0706-9583
J Steven AlexanderDepartment of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center in Shreveport, Shreveport, LA 71103, USA.ORCID 0000-0001-6975-3711
Louisiana State University Health Sciences Center Shreveport · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subarachnoid hemorrhage (SAH) is a type of hemorrhagic stroke resulting from the rupture of an arterial vessel within the brain. Unlike other stroke types, SAH affects both young adults (mid-40s) and the geriatric population. Patients with SAH often experience significant neurological deficits, leading to a substantial societal burden in terms of lost potential years of life. This review provides a comprehensive overview of SAH, examining its development across different stages (early, intermediate, and late) and highlighting the pathophysiological and pathohistological processes specific to each phase. The clinical management of SAH is also explored, focusing on tailored treatments and interventions to address the unique pathological changes that occur during each stage. Additionally, the paper reviews current treatment modalities and pharmacological interventions based on the evolving guidelines provided by the American Heart Association (AHA). Recent advances in our understanding of SAH will facilitate clinicians' improved management of SAH to reduce the incidence of delayed cerebral ischemia in patients.

Indexed as

AHAaneurysmcerebral vasospasmdelayed cerebral ischemiaendothelial dysfunctionglymphatic systemintramural periarterial drainageneuroinflammationpathophysiologysubarachnoid hemorrhage

Identifiers

PMID37755398
PMCPMC10536590
OpenAlexW4386741724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.