Evidence map›Paper›PMID 37755315›Full record

SynthesisPsychiatry and clinical neurosciences2024

Sense of agency and its disturbances: A systematic review targeting the intentional binding effect in neuropsychiatric disorders.

Lorenzo Moccia, Michelangelo di Luzio, Eliana Conte, Marco Modica, Marianna Ambrosecchia, Martina Ardizzi, Pierluigi Lanzotti, Georgios D Kotzalidis, Delfina Janiri, Marco Di Nicola and 3 more

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Psychiatry and clinical neurosciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Hypnotizability and Time Reproduction.Cerebellum (London, England) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Lorenzo MocciaDepartment of Neuroscience, Section of Psychiatry, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID https://orcid.org/0000-0003-3176-6060
Michelangelo di LuzioChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
Eliana ConteDepartment of Neuroscience, Section of Psychiatry, Università Cattolica del Sacro Cuore, Rome, Italy.
Marco ModicaDepartment of Neuroscience, Section of Psychiatry, Università Cattolica del Sacro Cuore, Rome, Italy.
Marianna AmbrosecchiaDepartment of Medicine and Surgery, Unit of Neuroscience, University of Parma, Parma, Italy.
Martina ArdizziDepartment of Medicine and Surgery, Unit of Neuroscience, University of Parma, Parma, Italy.
Pierluigi LanzottiDepartment of Neuroscience, Section of Psychiatry, Università Cattolica del Sacro Cuore, Rome, Italy.
Georgios D KotzalidisDepartment of Neuroscience, Section of Psychiatry, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID https://orcid.org/0000-0002-0281-6324
Delfina JaniriDepartment of Neuroscience, Section of Psychiatry, Università Cattolica del Sacro Cuore, Rome, Italy.
Marco Di NicolaDepartment of Neuroscience, Section of Psychiatry, Università Cattolica del Sacro Cuore, Rome, Italy.
Luigi JaniriDepartment of Neuroscience, Section of Psychiatry, Università Cattolica del Sacro Cuore, Rome, Italy.
Vittorio GalleseDepartment of Medicine and Surgery, Unit of Neuroscience, University of Parma, Parma, Italy.
Gabriele SaniDepartment of Neuroscience, Section of Psychiatry, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID https://orcid.org/0000-0002-9767-8752
Università Cattolica del Sacro Cuore · ITUniversity of Parma · ITBambino Gesù Children's Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sense of agency (SoA) indicates a person's ability to perceive her/his own motor acts as actually being her/his and, through them, to exert control over the course of external events. Disruptions in SoA may profoundly affect the individual's functioning, as observed in several neuropsychiatric disorders. This is the first article to systematically review studies that investigated intentional binding (IB), a quantitative proxy for SoA measurement, in neurological and psychiatric patients. Eligible were studies of IB involving patients with neurological and/or psychiatric disorders. We included 15 studies involving 692 individuals. Risk of bias was low throughout studies. Abnormally increased action-outcome binding was found in schizophrenia and in patients with Parkinson's disease taking dopaminergic medications or reporting impulsive-compulsive behaviors. A decreased IB effect was observed in Tourette's disorder and functional movement disorders, whereas increased action-outcome binding was found in patients with the cortico-basal syndrome. The extent of IB deviation from healthy control values correlated with the severity of symptoms in several disorders. Inconsistent effects were found for autism spectrum disorders, anorexia nervosa, and borderline personality disorder. Findings pave the way for treatments specifically targeting SoA in neuropsychiatric disorders where IB is altered.

Indexed as

Mental DisordersNervous System DiseasesPerceptionCompulsive BehaviorFemaleHumansImpulsive BehaviorParkinson DiseaseTourette Syndromeintentional bindingmood disordersParkinson's diseaseschizophreniasense of agency

Identifiers

PMID37755315
PMCPMC11488622
OpenAlexW4387060262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.